Estimation of Labetalol Hydrochloride in bulk and formulation by UV-Spectrophotometric Area Under Curve.

  • Akshada D. Suryawanshi Vishal Institute of Pharmaceutical Education and Research, Ale, Tal- Junnar, Pune (412411) Maharashtra, India
  • Shankar M. Dhobale Vishal Institute of Pharmaceutical Education and Research, Ale, Tal- Junnar, Pune (412411) Maharashtra, India
  • Suchita R. Abhang Vishal Institute of Pharmaceutical Education and Research, Ale, Tal- Junnar, Pune (412411) Maharashtra, India
  • Salim G. Patel Vishal Institute of Pharmaceutical Education and Research, Ale, Tal- Junnar, Pune (412411) Maharashtra, India

Abstract

The current work was carried out for estimation of labetalol hydrochloride in bulk and pharmaceutical dosage form by utilizing area under curve method (AUC) method .For this purpose the wavelength range 200-400 nm was selected .Distilled Water was used as a solvent throughout the work. The linearity was observed in concentration range 5-25 µg/ml (r2 =0.9788) for the method. The present was found which can be used for routine quality control analysis for spectrophotometric estimation of labetalol hydrochloride in bulk and dosage form.


Keywords: Labetalol hydrochloride, Area under curve (AUC), Distilled Water, UV Spectrophotometric.

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Author Biographies

Akshada D. Suryawanshi, Vishal Institute of Pharmaceutical Education and Research, Ale, Tal- Junnar, Pune (412411) Maharashtra, India

Vishal Institute of Pharmaceutical Education and Research, Ale, Tal- Junnar, Pune (412411) Maharashtra, India

Shankar M. Dhobale, Vishal Institute of Pharmaceutical Education and Research, Ale, Tal- Junnar, Pune (412411) Maharashtra, India

Vishal Institute of Pharmaceutical Education and Research, Ale, Tal- Junnar, Pune (412411) Maharashtra, India

Suchita R. Abhang, Vishal Institute of Pharmaceutical Education and Research, Ale, Tal- Junnar, Pune (412411) Maharashtra, India

Vishal Institute of Pharmaceutical Education and Research, Ale, Tal- Junnar, Pune (412411) Maharashtra, India

Salim G. Patel, Vishal Institute of Pharmaceutical Education and Research, Ale, Tal- Junnar, Pune (412411) Maharashtra, India

Vishal Institute of Pharmaceutical Education and Research, Ale, Tal- Junnar, Pune (412411) Maharashtra, India

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How to Cite
Suryawanshi, A. D., Dhobale, S. M., Abhang, S. R., & Patel, S. G. (2019). Estimation of Labetalol Hydrochloride in bulk and formulation by UV-Spectrophotometric Area Under Curve. Journal of Drug Delivery and Therapeutics, 9(3), 168-170. https://doi.org/10.22270/jddt.v9i3.2633