Simultaneous estimation of simvastatin and labetalol in bulk and solid dosage form

  • Abhijeet A. Sonawane
  • Akhil A. Shinde
  • Pooja K. Phalke Vishal Institute of Pharmaceutical Education & Research, Ale, Tal: Junnar Dist: Pune 412411 Maharashtra India
  • Nikita N. Bodke
  • Sonali D. Dangat
  • Neha A. Vishwakarma
  • S.L. Jadhav

Abstract

A simple, accurate, precise, sensitive, and highly selective ultra violet spectrometer method has been developed for the simultaneous estimation of simvastatin and labetalol in bulk and solid dosage form. The estimation of simvastatin was carried out at 239 nm while labetalol was estimated at 222.4 nm. The developed method was validated for linearity range, precision, recovery studies and interference study for mixture, all these parameter showed the adaptability of the method for the method quality analysis of the drug in bulk and combination formulation.


Keywords: Simvastatin, Labetalol, UV Spectrophotometric, Dosage form.

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Author Biography

Pooja K. Phalke, Vishal Institute of Pharmaceutical Education & Research, Ale, Tal: Junnar Dist: Pune 412411 Maharashtra India

Vishal Institute of Pharmaceutical Education & Research, Ale, Tal: Junnar Dist: Pune 412411 Maharashtra India

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How to Cite
Sonawane, A. A., Shinde, A. A., Phalke, P. K., Bodke, N. N., Dangat, S. D., Vishwakarma, N. A., & Jadhav, S. (2019). Simultaneous estimation of simvastatin and labetalol in bulk and solid dosage form. Journal of Drug Delivery and Therapeutics, 9(2-s), 383-386. https://doi.org/10.22270/jddt.v9i2-s.2532