A study on evaluation of risk factors and anti-microbial prophylaxis in the prevention of surgical site infection

  • Deepthi Shenoy Department of Pharmacy Practice, PES College of Pharmacy, Bengaluru, Karnataka, India-560 050.
  • Keerthana Nalluri Department of Pharmacy Practice, PES College of Pharmacy, Bengaluru, Karnataka, India-560 050.
  • C Manasa Department of Pharmacy Practice, PES College of Pharmacy, Bengaluru, Karnataka, India-560 050.
  • Pradeep Reddy Department of Pharmacy Practice, PES College of Pharmacy, Bengaluru, Karnataka, India-560 050.
  • R Srinivasan Department of Pharmacy Practice, PES College of Pharmacy, Bengaluru, Karnataka, India-560 050.

Abstract

Background: Surgical site infections are potential complications associated with a type of surgical procedure. Although surgical site infections are among the most preventable healthcare associated infections, they still represent a significant burden in terms of morbidity, mortality and addition costs to healthcare systems and service payers worldwide. Appropriate antibiotic prophylaxis has shown to be effective in reducing the incidence of surgical site infections.


Aim: The aim of the study is to carry out an evaluation of the risk factors and prophylactic antibiotics used to prevent surgical site infection in surgeries performed in an NABH accredited quaternary care hospital in Bengaluru, Karnataka.


Objective: To evaluate patient related risk factors contributing to the incidence of surgical site infection. To evaluate the prophylactic anti-biotic used in the prevention of post-operative surgical site infection and to determine the incidence of surgical site infection.


Methodology: Subjects who meet the study criteria will be enrolled in the study. Collection of patient related data with subsequent identification and evaluation of risk factors and prophylactic anti-biotics, and calculation of incidence of surgical site infection using statistical analysis.


Results: In this study, on observation of 372 surgical cases, it was estimated that 1 in 10 patients acquired Surgical Site Infection within 30 days post-surgery.


Conclusion: Conclusively, it can be said that the incidence of surgical site infection varies by different patient and procedure factors as well as prophylactic anti-biotic properties. They particularly show greater association to age, gender, certain comorbidities (like diabetes mellitus, chronic lung disease, and renal insufficiency), and duration of surgery, administration of prophylactic antibiotic, frequency, timing and dose. Therefore, greater care must be taken for every specific patient and procedure and also choice of antibiotic prophylaxis.

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Author Biographies

Deepthi Shenoy, Department of Pharmacy Practice, PES College of Pharmacy, Bengaluru, Karnataka, India-560 050.

Department of Pharmacy Practice, PES College of Pharmacy, Bengaluru, Karnataka, India-560 050.

Keerthana Nalluri, Department of Pharmacy Practice, PES College of Pharmacy, Bengaluru, Karnataka, India-560 050.

Department of Pharmacy Practice, PES College of Pharmacy, Bengaluru, Karnataka, India-560 050.

C Manasa, Department of Pharmacy Practice, PES College of Pharmacy, Bengaluru, Karnataka, India-560 050.

Department of Pharmacy Practice, PES College of Pharmacy, Bengaluru, Karnataka, India-560 050.

Pradeep Reddy, Department of Pharmacy Practice, PES College of Pharmacy, Bengaluru, Karnataka, India-560 050.

Department of Pharmacy Practice, PES College of Pharmacy, Bengaluru, Karnataka, India-560 050.

R Srinivasan, Department of Pharmacy Practice, PES College of Pharmacy, Bengaluru, Karnataka, India-560 050.

Department of Pharmacy Practice, PES College of Pharmacy, Bengaluru, Karnataka, India-560 050.

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How to Cite
Shenoy, D., Nalluri, K., Manasa, C., Reddy, P., & Srinivasan, R. (2019). A study on evaluation of risk factors and anti-microbial prophylaxis in the prevention of surgical site infection. Journal of Drug Delivery and Therapeutics, 9(2-s), 159-166. https://doi.org/10.22270/jddt.v9i2-s.2477