Pharmacological Activity of a Polyherbal Formulation by Haemoglobin Glycosylation Assay

  • Bhupendra Chauhan Adarsh Vijendra Institute of Pharmaceutical Sciences, Shobhit University, Gangoh (India)
  • Zulphikar Ali Adarsh Vijendra Institute of Pharmaceutical Sciences, Shobhit University, Gangoh (India)
  • Md. Arif Naseer Adarsh Vijendra Institute of Pharmaceutical Sciences, Shobhit University, Gangoh (India)
  • Ranjit Singh Adarsh Vijendra Institute of Pharmaceutical Sciences, Shobhit University, Gangoh (India)

Abstract

Present study involves the development of a polyherbal formulation by using four different herbs i.e. Chirata (Swertia chiratia), Haldi (Curcuma longa), Neem (Azadirachta indica), Gudmar (Gymnema sylvestre), Ashwagandha (Withania somnifera), Gokharu (Pedalium murex), Methi (Trigonella foenum-graecum), Jammun (Syzygium cumini), relating to antidiabetic activity. Freshly collected and authenticated herbs were characterized by studying its morphological and pharmacognostic character. Antidiabetic and antioxidant activity of the formulation was determined by in vitro haemoglobin glycosylation assay and H2O2 radical scavenging method respectively. In the above study it was found that ethanolic extract of polyherbal formulation possess promising antidiabetic and antioxidant activity which can be consider for further biological investigation.


Keywords: polyherbal formulation, Swertia chiratia, Curcuma longa, Azadirachta indica, Gymnema sylvestre, Withania somnifera, Pedalium murex, Trigonella foenum-graecum, Syzygium cumini

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Author Biographies

Bhupendra Chauhan, Adarsh Vijendra Institute of Pharmaceutical Sciences, Shobhit University, Gangoh (India)

Adarsh Vijendra Institute of Pharmaceutical Sciences, Shobhit University, Gangoh (India)

Zulphikar Ali, Adarsh Vijendra Institute of Pharmaceutical Sciences, Shobhit University, Gangoh (India)

Adarsh Vijendra Institute of Pharmaceutical Sciences, Shobhit University, Gangoh (India)

Md. Arif Naseer, Adarsh Vijendra Institute of Pharmaceutical Sciences, Shobhit University, Gangoh (India)

Adarsh Vijendra Institute of Pharmaceutical Sciences, Shobhit University, Gangoh (India)

Ranjit Singh, Adarsh Vijendra Institute of Pharmaceutical Sciences, Shobhit University, Gangoh (India)

Adarsh Vijendra Institute of Pharmaceutical Sciences, Shobhit University, Gangoh (India)

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How to Cite
Chauhan, B., Ali, Z., Naseer, M. A., & Singh, R. (2019). Pharmacological Activity of a Polyherbal Formulation by Haemoglobin Glycosylation Assay. Journal of Drug Delivery and Therapeutics, 9(2), 57-60. https://doi.org/10.22270/jddt.v9i2.2472