Phytochemical and in-vitro antioxidant activity of Careya arborea Roxb. leaves successive extracts

  • Shailaja D Wadje Department of Chemistry, Science College, Nanded, Maharashtra, India 43160
  • Balaji G Wankhede Aadarsh Jr. College, Manatha, Hadgoan, Nanded, Maharashtra, India 43160
  • Madhav R Mali Department of Chemistry, Yeshwant Mahavidyalya, Nanded, Maharashtra, India 43160

Abstract

The successive extracts of Careya arborea Roxb leaves, a traditional medicinal plant used in India. It possessed a significant amount of total phenolic and flavonoid contents with potent antioxidant activities in scavenging DPPH, ABTS radicals, and good total antioxidant capacity. On the other hand, the ethyl acetate and ethanol extracts showed the highest inhibition of DPPH, ABTS radicals and phosphomolybdate assay. This study verified that the ethyl acetate and ethanol extracts have strong antioxidant activities which might be due to high level of phenolics and flavonoids. Thus results confirm its traditional claims can be used as a source of potential antioxidant.


Keywords: Careya arborea Roxb, successive, leaves, antioxidant.

Downloads

Download data is not yet available.

Author Biographies

Shailaja D Wadje, Department of Chemistry, Science College, Nanded, Maharashtra, India 43160

Department of Chemistry, Science College, Nanded, Maharashtra, India 43160

Balaji G Wankhede, Aadarsh Jr. College, Manatha, Hadgoan, Nanded, Maharashtra, India 43160

Aadarsh Jr. College, Manatha, Hadgoan, Nanded, Maharashtra, India 43160

Madhav R Mali, Department of Chemistry, Yeshwant Mahavidyalya, Nanded, Maharashtra, India 43160

Department of Chemistry, Yeshwant Mahavidyalya, Nanded, Maharashtra, India 43160

References

1 Jeong C-H, Choi GN, Kim JH, Kwak JH, Kim DO, Kim YJ, Heo HJ. Antioxidant activities from the aerial parts of Platycodon grandiflorum. Food chemistry, 2010; 118:278-282.
2 Maheshwari J, Kalakoti B, Lal B. Ethnomedicine of Bhil tribe of Jhabua District, MP. Ancient Science of life, 1986; 5:255.
3 Das P, Misra M. Some ethnomedicinal plants of Koraput district Orissa. Ancient science of life, 1988;8:60.
4 Mahato S, Banerjee S, Chakravarti R. Taraxerol from Careya arborea. Bulletin of the Calcutta School of Tropical Medicine, 1967; 15:8-12.
5 Gupt R, Chakraborty N, Dutta T. Crystalline constituents from Careya arborea Roxb. Indian Journal Pharmay 1975;376:161-162.
6 Talapatra B, Basak A, Talapatra S. Terpenoids and related compounds. Part XX. Careaborin, a new triterpene ester from the leaves of Careya arborea. Journal of Indian Chemical Soceity, 1981; 58:814-815.
7 Kumar RS, Sivakumar T, Sundaram RS, Sivakumar P, Nethaji R, Gupta M. Antimicrobial and antioxidant activities of Careya arborea Roxb. Stem bark. Iranian Journal of Pharmacology & Therapeutics, 2006; 5:35-41.
8 Singleton V, Rossi JA. Colorimetry of total phenolics with phosphomolybdic-phosphotungstic acid reagents. American journal of Enology and Viticulture, 1965; 16:144-158.
9 Kalaskar MG, Surana SJ. Free radical scavenging and hepatoprotective potential of Ficus microcarpa L. fil. bark extracts. Journal of natural medicines, 2011; 65:633-640.
10 Ebrahimzadeh MA, Nabavi SM, Nabavi SF, Bahramian F, Bekhradnia AR. Antioxidant and free radical scavenging activity of H. officinalis L. var. angustifolius, V. odorata, B. hyrcana and C. speciosum. Pak J Pharm Sci, 2010; 23:29-34.
11 Fellegrini N, Ke R, Yang M, Rice-Evans C. [34] Screening of dietary carotenoids and carotenoid-rich fruit extracts for antioxidant activities applying 2, 2′-azinobis (3-ethylenebenzothiazoline-6-sulfonic acid radical cation decolorization assay. Methods in enzymology, 1999; 299:379-389.
12 Abdel-Hameed E-SS. Total phenolic contents and free radical scavenging activity of certain Egyptian Ficus species leaf samples. Food Chemistry, 2009; 114:1271-1277.
13 Sharififar F, Dehghn-Nudeh G, Mirtajaldini M. Major flavonoids with antioxidant activity from Teucrium polium L. Food Chemistry, 2009; 112:885-888.
14 Bahramikia S, Ardestani A, Yazdanparast R. Protective effects of four Iranian medicinal plants against free radical-mediated protein oxidation. Food Chemistry, 2009; 115:37-42.
15 Soare JR, Dinis TC, Cunha AP, Almeida L. Antioxidant activities of some extracts of Thymus zygis. Free radical research, 1997;26:469-478.
16 Sancez-Moreno C. Methods used to evaluate the free radical scavenging activity in foods and biologic systems-review. Food Science and Technology International, 2002; 8:121-137.
17 Adedapo AA, Jimoh FO, Koduru S, Afolayan AJ, Masika PJ. Antibacterial and antioxidant properties of the methanol extracts of the leaves and stems of Calpurnia aurea. BMC Complementary and alternative medicine, 2008; 8:1.
18 Magalhães LM, Segundo MA, Reis S, Lima JL. Methodological aspects about in vitro evaluation of antioxidant properties. Analytica chimica acta, 2008; 613:1-19.
19 Duh P-D, Yen G-C. Antioxidative activity of three herbal water extracts. Food Chemistry, 1997; 60:639-645.
20 Povichit N, Phrutivorapongkul A, Suttajit M, Chaiyasut C, Leelapornpisid P. Phenolic content and in vitro inhibitory effects on oxidation and protein glycation of some Thai medicinal plants. Pak J Pharm Sci, 2010; 23:403-408.
21 Prieto P, Pineda M, Aguilar M. Spectrophotometric quantitation of antioxidant capacity through the formation of a phosphomolybdenum complex: specific application to the determination of vitamin E. Analytical biochemistry, 1999; 269:337-341.
22 Pan Y, Wang K, Huang S, Wang H, Mu X, He C, Ji X, Zhang J, Huang F. Antioxidant activity of microwave-assisted extract of longan (Dimocarpus Longan Lour.) peel. Food Chemistry, 2008;106:1264-1270.
23 Tunalier Z, Kosar M, Ozturk N, Baser K, Duman H, Kirimer N. Antioxidant properties and phenolic composition of Sideritis species. Chemistry of natural compounds, 2004; 40:206-210.
24 González-Burgos E, Carretero M, Gómez-Serranillos M. Sideritis spp.: uses, chemical composition and pharmacological activities—a review. Journal of ethnopharmacology, 2011; 135:209-225.
25 Javanmardi J, Stushnoff C, Locke E, Vivanco J. Antioxidant activity and total phenolic content of Iranian Ocimum accessions. Food chemistry, 2003; 83:547-550.
Statistics
10 Views | 8 Downloads
How to Cite
Wadje, S. D., Wankhede, B. G., & Mali, M. R. (2019). Phytochemical and in-vitro antioxidant activity of Careya arborea Roxb. leaves successive extracts. Journal of Drug Delivery and Therapeutics, 9(2-s), 53-56. https://doi.org/10.22270/jddt.v9i2-s.2454