A study to assess drug related problems in patients with Cardiovascular Diseases in a tertiary care teaching hospital
Back ground: Drug related problems are common in hospitalized patients and may lead to increase hospital stay, health care cost and augment the risk of morbidity and mortality.
Objective: The aim of the study is to examine the nature and frequency of drug related problems, to minimize drug related problems and to improve therapeutic outcome by pharmaceutical care provided by clinical pharmacist.
Methodology: A prospective study was conducted in the cardiology department of a tertiary care hospital over a period of six months. Necessary demographic and clinical data was collected from the case records including drug history, other relevant details of the admitted patients and reviewed by the clinical pharmacist for drug related problems.
Results: A total of 280 patient case sheets were reviewed during the study period, out of which 244 drug related problems were identified. The most common drug related problem was found to be drug interactions (58.6%) followed by untreated indication (19.26%) and drug use without indication (15.57%). The most frequent suggestions provided by the intervening pharmacist were drug discontinuation (5.32%), addition of a new drug (5.32%) and change of dosage form (4.5%).
Conclusion: Drug related problems are common among medical ward patients. Routine participation of clinical pharmacist in clinical medical rounds facilitates the identification of drug related problems and the current study highlights the importance of pharmacist in a multidisciplinary team of reviewing drug therapy for identification and resolution of DRPs which helps in achieving better therapeutic outcomes and improved patient care.
Keywords: cardiovascular diseases, clinical pharmacist, dyslipidemia, drug related problem.
2. Rani Reema Abraham. Drug related problems and reactive pharmacists interventions for inpatients receiving cardio vascular drugs. International journal of basic medical sciences and pharmacy 2013; 3(2):2049-4963.
3. Viktil KK, Blix HS. The impact of clinical pharmacists on drug related problems and clinical outcomes. Clin Pharmacol Toxicol 2008; 102(3):275-80.
4. Ragesh G, Sindhubharathi A, Usharani M, Srinivasulu A. Assessment of clinical pharmacy services to cardiology department in tertiary care teaching hospital. International journal of pharmacy and pharmaceutical sciences 2014; 6(2):0975-1491.
5. Gashaw Binega Meknonnen, Mequanent Kassa Biarra, Masho Tigabe Tekle, Akshaya Srikanth Bhagavathula. Assessment of Drug Related Problems and its Associated Factors among Medical Ward Patients in University of Gondar Teaching Hospital, Northwest Ethiopia: A Prospective Cross-Sectional Study. Journal of Basic and Clinical Pharmacy 2017; 8: 016-21.
6. Zieske AW, Malcom GT, Strong JP. Natural history and risk factors of atherosclerosis in children and youth: The PDAY study. Pediatr Pathol Mol Med 2002; 21(2):213-37.
7. Celin AT, Seuma J, Ramesh A. Assessment of drug related problems in stroke patients admitted to a south Indian tertiary care teaching hospital. Indian J Pharm Pract 2012; 5(4):28–33.
8. Alagiriswami B, Ramesh M, Parthasarathi G, Basavanagow dappa H. Clinical pharmacist initiated changes in drug therapy in a teaching hospital. Indian J Pharm Pract 2009; 1(2):36-45.
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
Authors who publish with this journal agree to the following terms:
- Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License. that allows others to share the work with an acknowledgment of the work's authorship and initial publication in this journal.
- Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgment of its initial publication in this journal.
- Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (SeeÂ The Effect of Open Access).