Synthesis, characterization and thrombolytic activity of n-benzyl piperidin 4-one phenyl hydrazone

  • K. Sundaresan Dept of Chemistry, GOVT Arts College, Trichy-22, Tamil Nadu, India
  • V. Priyadarshini Dept of Chemistry, GOVT Arts College, Trichy-22, Tamil Nadu, India
  • K. Tharini Dept of Chemistry, GOVT Arts College, Trichy-22, Tamil Nadu, India

Abstract

The aim of this study was to synthesize, characterization and thrombolytic activity of    N-Benzyl piperidin 4-one phenyl hydrazone derivative. Check the purity of all the synthesized compounds using thin layer chromatography. The synthesized compound was characterized by IR, 13C and 1H NMR spectral studies. The synthesized compound was subjected to thrombolytic activity. The thrombolytic activity was observed in 2 different concentrations of N-Benzyl piperidin 4-one phenyl hydrazone. Our findings support the reported therapeutic use of this compound as a thrombolytic agent in the Indian system of medicine.


Keywords: N-Benzyl piperidin 4-one phenyl hydrazone, thrombolytic activity, streptokinase.

Downloads

Download data is not yet available.

Author Biographies

K. Sundaresan, Dept of Chemistry, GOVT Arts College, Trichy-22, Tamil Nadu, India

Dept of Chemistry, GOVT Arts College, Trichy-22, Tamil Nadu, India

V. Priyadarshini, Dept of Chemistry, GOVT Arts College, Trichy-22, Tamil Nadu, India

Dept of Chemistry, GOVT Arts College, Trichy-22, Tamil Nadu, India

K. Tharini, Dept of Chemistry, GOVT Arts College, Trichy-22, Tamil Nadu, India

Dept of Chemistry, GOVT Arts College, Trichy-22, Tamil Nadu, India

Statistics
78 Views | 145 Downloads
How to Cite
Sundaresan, K., Priyadarshini, V., & Tharini, K. (2019). Synthesis, characterization and thrombolytic activity of n-benzyl piperidin 4-one phenyl hydrazone. Journal of Drug Delivery and Therapeutics, 9(2), 180-182. https://doi.org/10.22270/jddt.v9i2.2393