Application of Nanoparticles for Brain and Lung Cancer Therapeutics

  • Xialin Chen State Key Laboratory of New-tech for Chinese Medicine Pharmaceutical Process, Jiangsu Kanion Pharmaceutical Co. Ltd., Lianyungang, 222001, China

Abstract

Nanotechnology is and will be the future of several fields and medicine is one of them. The use of nanoparticles in the treatment of psychotic and cancer problems is analyzed in this report. Psychotic treatment has been effective due to specific nanoparticles like haloperidol and RISP, and these combinations are linked with other nanoparticles to treat other diseases. Nanoparticles have extended applications with a high degree of effectiveness to treat cancer cells due to the quick delivery, and targeted process and the same is detailed in the review sheet. Oligonucleotides combined with nanoparticles have greater efficiencies.


Keywords: Nanotechnology, drug targeting, cancer treatment

Downloads

Download data is not yet available.

Author Biography

Xialin Chen, State Key Laboratory of New-tech for Chinese Medicine Pharmaceutical Process, Jiangsu Kanion Pharmaceutical Co. Ltd., Lianyungang, 222001, China

State Key Laboratory of New-tech for Chinese Medicine Pharmaceutical Process, Jiangsu Kanion Pharmaceutical Co. Ltd., Lianyungang, 222001, China

References

1. Qiao, H., et al. Redox-triggered mitoxantrone prodrug micelles for overcoming multidrug-resistant breast cancer. Journal of drug targeting 26, 75-85 (2018).
2. Kang, C., Qin, J., Osei, W. & Hu, K. Regulation of protein kinase C-epsilon and its age-dependence. Biochemical and Biophysical Research Communications 482, 1201-1206 (2017).
3. Sun, Y., et al. RGD Peptide‐Based Target Drug Delivery of Doxorubicin Nanomedicine. Drug development research 78, 283-291 (2017).
4. Kang, C. & Hu, K. Role of caveolin-3 in adenosine-induced increase in mitochondrial PKCε. The FASEB Journal 27, 1191.1197-1191.1197 (2013).
5. Cheng, X. & Lee, R.J. The role of helper lipids in lipid nanoparticles (LNPs) designed for oligonucleotide delivery. Adv Drug Deliv Rev 99, 129-137 (2016).
6. Sun, Y. & Kang, C. Self-Assembly of Peptides into Hydrogel. Journal of Organic & Inorganic Chemistry 2, 5 (2016).
7. Yao, Z., Sun, Y. & Kang, C. Structure and self-assembly of multicolored Naphthalene Diimides Semiconductor. Nano LIFE 6, 1642007 (2016).
8. Cheng, X., et al. T7 Peptide-Conjugated Lipid Nanoparticles for Dual Modulation of Bcl-2 and Akt-1 in Lung and Cervical Carcinomas. Molecular pharmaceutics 15, 4722-4732 (2018).
9. Zhong, X., Sun, Y., Kang, C. & Wan, G. The theory of dielectrophoresis and its applications on medical and materials research. European Journal of BioMedical Research 2, 7-11 (2017).
10. Kang, C. & Hu, K. Modulation of the two-pore domain potassium channel TASK-1 by caveolin-3. The FASEB Journal 29, 845.814 (2015).
11. Davis, M.E., Chen, Z.G. & Shin, D.M. Nanoparticle therapeutics: an emerging treatment modality for cancer. Nat Rev Drug Discov 7, 771-782 (2008).
12. Kang, C., Sun, Y., Wang, M. & Cheng, X. Nanosized camptothecin conjugates for single and combined drug delivery. European Journal of BioMedical Research 2, 8-14 (2016).
13. Qiao, H., et al. Orally delivered polycurcumin responsive to bacterial reduction for targeted therapy of inflammatory bowel disease. Drug Delivery 24, 233-242 (2017).
14. Liu, F., Sun, Y., Kang, C. & Zhu, H. Pegylated Drug Delivery Systems: From Design to Biomedical Applications. Nano LIFE 6, 1642002 (2016).
15. Sun, Y., Kang, C., Yao, Z., Liu, F. & Zhou, Y. Peptide-Based Ligand for Active Delivery of Liposomal Doxorubicin. Nano Life 6, 1642004 (2016).
16. Yeh, C.Y., Hsiao, J.K., Wang, Y.P., Lan, C.H. & Wu, H.C. Peptide-conjugated nanoparticles for targeted imaging and therapy of prostate cancer. Biomaterials 99, 1-15 (2016).
17. Li, Q., et al. Identification by shape-based virtual screening and evaluation of new tyrosinase inhibitors. PeerJ 6, e4206 (2018).
18. Chen, Y., et al. Identification of 4-aminoquinoline core for the design of new cholinesterase inhibitors. PeerJ 4, e2140 (2016).
19. Kang, C. & Hu, K. Impact of hypoxia in the expression and regulation of the TASK-1 potassium channel in cardiac myocytes. The FASEB Journal 30, lb598-lb598 (2016).
20. Kang, C. Ion channels, protein kinase C and caveolae in cardioprotection, (The Ohio State University, 2015).
21. Yung, B.C., et al. Lipid nanoparticles composed of quaternary amine–tertiary amine cationic lipid combination (QTsome) for therapeutic delivery of AntimiR-21 for lung cancer. Molecular pharmaceutics 13, 653-662 (2016).
22. Cheng, X., et al. Lipid Nanoparticles Loaded with an Antisense Oligonucleotide Gapmer Against Bcl-2 for Treatment of Lung Cancer. Pharmaceutical research 34, 310-320 (2017).
23. Fan, S. & Chi, W. Methods for genome-wide DNA methylation analysis in human cancer. Brief Funct Genomics 15, 432-442 (2016).
24. Peng, J., et al. Enhanced Liver Regeneration After Partial Hepatectomy in Sterol Regulatory Element-Binding Protein (SREBP)-1c-Null Mice is Associated with Increased Hepatocellular Cholesterol Availability. Cellular Physiology and Biochemistry 47, 784-799 (2018).
25. Yang, Z., et al. Functional exosome-mimic for delivery of siRNA to cancer: in vitro and in vivo evaluation. Journal of Controlled Release 243, 160-171 (2016).
26. Kang, C., Hernandez, V.A. & Hu, K. Functional interaction of the two-pore domain potassium channel TASK-1 and caveolin-3. Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1864, 1537-1544 (2017).
27. Waller, A.P., et al. GLUT12 functions as a basal and insulin-independent glucose transporter in the heart. Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1832, 121-127 (2013).
28. Sun, Y., Kang, C., Liu, F. & Song, L. Delivery of antipsychotics with nanoparticles. Drug Development Research 77, 393-399 (2016).
29. Kang, C., et al. Delivery of nanoparticles for treatment of brain tumor. Current Drug Metabolism 17, 745-754 (2016).
30. Xue, X., et al. Discovery of novel inhibitors disrupting HIF-1α/von Hippel–Lindau interaction through shape-based screening and cascade docking. PeerJ 4, e2757 (2016).
31. Hersch, S.J., et al. Divergent protein motifs direct elongation factor P-mediated translational regulation in Salmonella enterica and Escherichia coli. MBio 4, e00180-00113 (2013).
32. Shuhong, X., et al. Dynamic expression of AQP4 in early stageof ischemia/reperfusion rats and cerebral edema. Chinese Pharmacological Bulletin 32, 1433-1441 (2016).
33. Duan, Y., et al. Bioactivity evaluation-based ultra high-performance liquid chromatography coupled with electrospray ionization tandem quadrupole-time-of-flight mass spectrometry and novel distinction of multi-subchemome compatibility recognition strategy with Astragali Radix-Fructus Corni herb-pair as a case study. J Pharm Biomed Anal 129, 514-534 (2016).
34. Sun, Y., et al. Co-delivery of dual-drugs with nanoparticle to overcome multidrug resistance. European Journal of BioMedical Research 2, 12-18 (2016).
35. Ai, R., et al. Comprehensive epigenetic landscape of rheumatoid arthritis fibroblast-like synoviocytes. Nat Commun 9, 1921 (2018).
36. Fan, S., et al. Computationally expanding infinium HumanMethylation450 BeadChip array data to reveal distinct DNA methylation patterns of rheumatoid arthritis. Bioinformatics 32, 1773-1778 (2016).
37. Liu, F., Sun, Y. & Kang, C. Controlling Amphiphilic Functional Block Copolymers’ Self-Assembly: From Structure to Size. (2016).
38. Song, L., et al. Crocetin inhibits lipopolysaccharide-induced inflammatory response in human umbilical vein endothelial cells. Cellular Physiology and Biochemistry 40, 443-452 (2016).
39. Kang, C., Qin, J., Osei, W. & Hu, K. Age-dependent Mitochondrial Targeting Of Protein Kinase C Epsilon In Cardioprotection. The FASEB Journal (2017).
40. Han, R., Sun, Y., Kang, C., Sun, H. & Wei, W. Amphiphilic dendritic nanomicelle-mediated co-delivery of 5-fluorouracil and doxorubicin for enhanced therapeutic efficacy. Journal of Drug Targeting 25, 140-148 (2017).
Statistics
93 Views | 124 Downloads
How to Cite
Chen, X. (2019). Application of Nanoparticles for Brain and Lung Cancer Therapeutics. Journal of Drug Delivery and Therapeutics, 9(1-s), 384-386. https://doi.org/10.22270/jddt.v9i1-s.2337