Evaluation of anti-microbial and anti-haemolytic activity of edible basidiomycetes mushroom fungi
Mushrooms are used for a variety of biotechnological applications, particularly for the production of food, enzymes, dietary supplements, pharmaceutical compounds, feed supplements. Basidiomycetes mushroom fungi have been known for their nutritional values they can be considered as functional foods which can provide health benefits beyond the traditional nutrients. Mushroom represents a major and untapped source of potent new pharmaceutical products. A wide range of activities including antitumour, cardiovascular and antimicrobial are reported in mushrooms. In developing countries like India mushroom progress is a boon in the field of food, medicine, and in generating employment. The alternative systems of medicine utilize the curative properties of mushrooms. They are also known to possess promising antioxidative, cardiovascular, hypercholesterolemia, antimicrobial, hepato-protective and anticancer effects. The present study aimed to evaluate antimicrobial and antihaemolytic activities of various extracts of Basidiomycetes mushroom fungi. Different Basidiomycetes mushroom fungi extracts (Hot water, Acetone and Hexane) were tested for antimicrobial and antihaemolytic activities. Among these different extracts of Basidiomycetes mushroom fungi the hexane extract of Pleurotus pulmonarius showed potential antimicrobial and antihaemolytic activity. The results of this study suggest the possibility of using Basidiomycetes mushroom fungi as natural sources for the pharmaceutical industry and could act as safe and cost-effective with potential biological activities. These findings encourage studying these fungal strains further for their potential biological applications.
2. Jones S, Janardhanan KK, Antioxidant and antitumor activity of Ganoderma lucidum (Cart. Fr.) P.Karst.-Reishi (Aphyllophoromycetidae) from South India, International Journal of Medicinal Mushroom, 2000; 2:195-200.
3. Agahar Murugkar D, Subbulakshmi G. Nutritional value of edible wild mushrooms collected from the Khasi hills of Meghalaya, Food Chemistry, 2005; 89:599-603.
4. Boa E, Wild Edible Fungi, A Global Overview of Their Use and Importance to People, Non-wood Forest Products Series no. 17, FAO, Rome, 2004; 147.
5. Karwa A, Rai M, Mycoenhancing the potential of synthetic antibiotics using wild mushrooms: First report. Proc. 5th Int. Medicinal Mushroom Conference, Mycological Society of China, Nantong, China, 2009; 167-172.
6. Breene W, Nutritional and medical value of speciality mushrooms, Journal of Food Products Marketing, 1990; 53:883-894.
7. Chihara G, Immunopharmacology of lentinan, a polysaccharide isolated from Lentinus edodes: its application as a host defense potentiator, International Jouranl of Oriental Medicince, 1992; 17:57-77.
8. Ooi VEC, Liu F, A review of pharmacological activities of mushroom polysaccharides. International Journal of Medicinal Mushrooms, 1999; 1:195-206.
9. Wasser SP, Weiss AL,. Medicinal properties of substances occurring in higher Basidiomycetes mushrooms: current perspectives. International Journal of Medicinal Mushrooms, 1999, 31:31-62.
10. Biswas G, Sarkar S, Acharya K, Free radical scavenging and anti-inflammatory activities of the extracts of Astraeus hygrometricus (Pers.) Morg., Latin American Journal of Pharmacy, 2010; 29(4):549-553.
11. Samorini G, Fungi Hallucinogeni. Studi etnomicologici. Telesterion. Dozza Ed., Bologna, Italy, Shen (Guo J, Cheng HY, Wei X. eds.), 2001; 250.
12. Gunde-Cimmerman N, Freidrich J, Cimmerman A, Benicki N, Screening fungi for the production of an inhibitor of HMG CoA reductase, production of mevinolin by the fungi of the genus Pleurotus, FEMS Microbiology Letters, 1993; 111:203-206.
13. Gunde-Cimmerman N, Medicinal value of the genus Pleurotus (Fr.) P. Kaest. (Agaricales S.l., Basidiomycetes), International Journal of Medicinal Mushrooms, 1999; 1:69-80.
14. Wasser SP, Medicinal mushrooms as source of antitumor and immunomodulating polysaccharides, Applied Microbiology and Biotechnology, 2002; 60: 258-274.
15. Chang ST, Global impact edible and medicinal mushrooms on human welfare in the 21st century: Non green evolution, International Journal of Medicinal Mushrooms, 1999; 1:1-7.
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
Authors who publish with this journal agree to the following terms:
- Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License. that allows others to share the work with an acknowledgment of the work's authorship and initial publication in this journal.
- Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgment of its initial publication in this journal.
- Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).