The In-vitro studies and evaluation of telmisartan marketed tablets

  • Jayendra Singh Bayas JSPM’s Charak College of Pharmacy and research, Pune 412207, Maharashtra, India.
  • Rameshwar Sanjabrao Cheke Asst. Professor
  • Prachi Lokhande JSPM’s Charak College of Pharmacy and research, Pune 412207, Maharashtra, India.
  • Santosh Waghmare JSPM’s Charak College of Pharmacy and research, Pune 412207, Maharashtra, India.
  • Shivshankar Gunjegaonkar JSPM’s Charak College of Pharmacy and research, Pune 412207, Maharashtra, India.
  • Sachin Shinde Department of pharmacology, Shri R D Bhakt college of pharmacy, Jalna, 431203, Maharashtra, India.

Abstract

Tablets or capsules taken orally remain one of the most effective means of treatment available. The effectiveness of such dosage forms relies on the drug dissolving in the fluids of the gastrointestinal tract prior to absorption into the systemic circulation. The present study reveals the evaluation of four marketed sample of Telmisartan tablets. The main aim of the study is to conduct dissolution test on the tablets to determine the compliance with a given official monograph. Four different marketed samples of Telmisartan were purchased from local market. The Telmisartan tablets were evaluated for the various in-vitro tablet properties such as thickness, hardness, friability, weight variation, drug content, disintegration time and dissolution rate. In-vitro dissolution test is conducted on four different brands of telmisartan tablets to assess their equivalency. All the four marketed samples of Telmisartan have shown good tablet properties and comply with the pharmacopoeial specification. The in- vitro dissolution showed the 80% drug release within one hour from all the four brands which complies with the specification of pharmacopoeia.

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Author Biographies

Jayendra Singh Bayas, JSPM’s Charak College of Pharmacy and research, Pune 412207, Maharashtra, India.

JSPM’s Charak College of Pharmacy and research, Pune 412207, Maharashtra, India.

Prachi Lokhande, JSPM’s Charak College of Pharmacy and research, Pune 412207, Maharashtra, India.

 JSPM’s Charak College of Pharmacy and research, Pune 412207, Maharashtra, India.

Santosh Waghmare, JSPM’s Charak College of Pharmacy and research, Pune 412207, Maharashtra, India.

JSPM’s Charak College of Pharmacy and research, Pune 412207, Maharashtra, India.

Shivshankar Gunjegaonkar, JSPM’s Charak College of Pharmacy and research, Pune 412207, Maharashtra, India.

JSPM’s Charak College of Pharmacy and research, Pune 412207, Maharashtra, India.

Sachin Shinde, Department of pharmacology, Shri R D Bhakt college of pharmacy, Jalna, 431203, Maharashtra, India.

Department of pharmacology, Shri R D Bhakt college of pharmacy, Jalna, 431203, Maharashtra, India.

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How to Cite
Bayas, J. S., Cheke, R., Lokhande, P., Waghmare, S., Gunjegaonkar, S., & Shinde, S. (2019). The In-vitro studies and evaluation of telmisartan marketed tablets. Journal of Drug Delivery and Therapeutics, 9(1), 74-78. https://doi.org/10.22270/jddt.v9i1.2267