Extracts of Ailanthus excels an Essential Medicine in Ayurveda: Pharmacological evaluationand preliminary screening of phytochemicals
Ailanthus excels belongs to family Simaroubaceae known as tree of Heaven and Mahanimba commonly found in the India and China. The present study involves preliminary screening, qualitative analysis and pharmacological evaluation of extract. The preliminary photochemical screening performed using petroleum ether, chloroform and methanol extract. Analytical techniques like; TLC, FTIR and HPTLC also performed for qualitative and quantitative determination. Various chemical tests also performed for qualitative determination of alkaloids, flavanoids, phenols, terpenoids, steroids and saponins in plant extracts. Plant extract finally subjected to antibacterial and antifungal activities and findings of study suggested that plant extracts possesses potent antibacterial and antifungal activities.
Keywords: Ailanthus excelsa, antibacterial, antifungal, preliminary screening, TLC, HPTLC.
2. Kumar D, Bhatt ZA, Singh P, Khatanglakar and S. S. Bhujbal, Anti-Asthmatic and Anti-Allergic Potential of Methanolic Extract of Leaves of Ailanthus ExcelsaRoxb. RevistaBrasileira de Farmacognozia, Brazilian J. Pharmacognosy, 2011; 21(1):139-145.
3. Ratha RR, Shamkuwar PB, Pawar DP, Antifungal Study of Ailanthus Excelsa Leaves, J. Chem. Pharm. Res., 2013; 5(6):152-154.
4. Anonymous, The Wealth of India: Raw Materials. Council of Industrial and Scientific Research, New Delhi (1956).
5. Shrimali M, Jain DC, Darokar MP, Sharma RP, Antibacterial Activity of Ailanthus Excelsa (Roxb.), Phytotherapy Research, 2001; 15(2):165-166.
6. Kirtikar KR, Basu BD, Indian Medicinal Plants, Int. Book Distributors, Dehradun, India, 1 (1995) pp. 371-372.
7. Kokate CK, Purohit AP, Gokhale SB, Pharnacognosy, 7th Edn., NiraliPrakashan (1997) pp. 105-144.
8. Indian Pharmacopoeia, 3rd Edn., Controller of Publication, Govt. of India, New Delhi, 2 (1985) pp. A88-A90.
9. Indian Pharmacopoeia, Vol. II 4th Edn., Controller of Publication, Govt. of India, New Delhi (1996) p. A-47.
10. K. R. Khandelwal, Practical Pharnacognosy, NiraliPrakashan, Pune, 9th Edition (2002) pp. 157-158.
11. Jayshree D. P. and Kumar V. Annonasquamosa L., Phytochemical analysis and antimicrobial screening, Journal of pharmacy research. 2008; 1(1):34-38.
12. Demirdöven N. Cheatum C. M. Chung H. S. Khalil M. Knoester J. Tokmakoff A. "Two-dimensional infrared spectroscopy of antiparallel beta-sheet secondary structure". Journal of the American Chemical Society. 2004; 126(25):7981–90.
13. Crombie D.S. and ChmurzynskiL. High-performance liquid chromatographic determination of quinine in rat biological fluids. J Chromatogra. B: Biomed Sci Appl. 1997; 693:423-429.
14. Ravishankara M.N. Shrivastava N. Padh H. and Rajani M. HPTLC Method for the Estimation of Alkaloids of Cinchona officinalis Stem Bark and its Marketed Formulations. Planta Med. 2001; 67:294-296.
15. Mroczek T. and Glowniak K. TLC and HPTLC assay of quinoline and quinuclidine alkaloids in Cinchona cortex and pharmaceutical preparations. J Planar Chromatogr. 2000; 13:457-462.
16. Sutar N, Garai R, Sharma US, Sharma UK. Anthelmintic activity of Platycladusorientalis leaves extract. International Journal of Parasitology Research 2010; 2(2):1-3.
17. Shete S. A. Shah G. N. Walke S. S. Patil V. S. Patil K. D. and Killedar S. G. Standardization and Antibacterial Activity of CouroupitaGuianensis Fruit Shell Extract, Int. J. Bioassays, 2013; 2(1):360-364.
18. Manikandan A. Rajendran R. Balachandar S. Sanumol M.S. and Mary S.M. Antimicrobial activity of ailanthus excels roxb. collected from coimbatore district, tamilnadu, india. 2015; 4(03):697-704.
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
Authors who publish with this journal agree to the following terms:
- Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License. that allows others to share the work with an acknowledgment of the work's authorship and initial publication in this journal.
- Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgment of its initial publication in this journal.
- Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (SeeÂ The Effect of Open Access).