In vitro study on screening antimicrobial and anti-oxidant potential of Ramalina fastigiata

  • Sureshrajan Soundararajan Department of Biotechnology, K.S. Rangasamy College of Technology, Tiruchengode - 637 215, Namakkal District, Tamil Nadu, India.
  • Poornima Shanmugam Department of Biotechnology, K.S. Rangasamy College of Technology, Tiruchengode - 637 215, Namakkal District, Tamil Nadu, India.
  • Nagarjun Nagarajan Department of Biotechnology, K.S. Rangasamy College of Technology, Tiruchengode - 637 215, Namakkal District, Tamil Nadu, India.
  • Divya Palanisamy Department of Biotechnology, K.S. Rangasamy College of Technology, Tiruchengode - 637 215, Namakkal District, Tamil Nadu, India.
  • Ponmurugan Ponnusamy Department of Botany, Bharathiar University, Coimbatore - 641 046, Tamil Nadu, India.

Abstract

The aim of the present study is to investigate the antimicrobial and anti-oxidant potential of lichen Ramalina fastigiata collected from Kolli hills, Eastern Gahts of Tamil Nadu, India. Phytochemical study revealed that acetone extract of Ramalina fastigiata confirmed the presence of flavonoids, glycosides and phenols. Acetone extract of Ramalina fastigiata was tested against human pathogens, which exposed antimicrobial activity against Klebsiella pneumonia and Candida krusei with the inhibition rate of 2.1 mm and 1.3 mm respectively. The acetone extract of lichen Ramalina fastigiata exhibited significant antioxidant activity as well. Radical scavenging ability of Ramalina fastigiata was reported in terms of 61.53 % inhibition.


Keywords: Lichen, Ramalina fastigiata, acetone extract, antimicrobial activity, anti-inflammatory potential

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Author Biographies

Sureshrajan Soundararajan, Department of Biotechnology, K.S. Rangasamy College of Technology, Tiruchengode - 637 215, Namakkal District, Tamil Nadu, India.

Department of Biotechnology, K.S. Rangasamy College of Technology, Tiruchengode - 637 215, Namakkal District, Tamil Nadu, India.

Poornima Shanmugam, Department of Biotechnology, K.S. Rangasamy College of Technology, Tiruchengode - 637 215, Namakkal District, Tamil Nadu, India.

Department of Biotechnology, K.S. Rangasamy College of Technology, Tiruchengode - 637 215, Namakkal District, Tamil Nadu, India.

Nagarjun Nagarajan, Department of Biotechnology, K.S. Rangasamy College of Technology, Tiruchengode - 637 215, Namakkal District, Tamil Nadu, India.

Department of Biotechnology, K.S. Rangasamy College of Technology, Tiruchengode - 637 215, Namakkal District, Tamil Nadu, India.

Divya Palanisamy, Department of Biotechnology, K.S. Rangasamy College of Technology, Tiruchengode - 637 215, Namakkal District, Tamil Nadu, India.

Department of Biotechnology, K.S. Rangasamy College of Technology, Tiruchengode - 637 215, Namakkal District, Tamil Nadu, India.

Ponmurugan Ponnusamy, Department of Botany, Bharathiar University, Coimbatore - 641 046, Tamil Nadu, India.

Department of Botany, Bharathiar University, Coimbatore - 641 046, Tamil Nadu, India.

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How to Cite
Soundararajan, S., Shanmugam, P., Nagarajan, N., Palanisamy, D., & Ponnusamy, P. (2019). In vitro study on screening antimicrobial and anti-oxidant potential of Ramalina fastigiata. Journal of Drug Delivery and Therapeutics, 9(1), 216-219. https://doi.org/10.22270/jddt.v9i1.2217