Pattern of analgesic use in hospitalized children at a pediatric general ward in a tertiary care teaching hospital
Abstract
Background: analgesic use is common in adults but their use in children has not been extensively studied. This observational study was envisaged to study prevalence and pattern of analgesic use in hospitalized children in pediatric general ward.
Methods: 120 patients were included in the study. Disease was classified as per ICD-10 and medicines used were classified according to ATC classification. WHO indicators for rationality was used. Descriptive statistics was used to present the data i.e. percentage; proportions, frequency, mean and standard deviation using Microsoft excel worksheet.
Result: A total of 791 drugs from different classes were prescribed to 120 patients with a mean of 6.6 + 2.68 drugs described per patient during their stay in the hospital. 81 analgesics were prescribed. 25 were prescribed as fixed dose combination. Paracetamol was the most commonly prescribed non steroidal anti-inflammatory agent.
Keywords: analgesics, children, fixed dose combinations
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References
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6. Neubert A, Verhamme K, Murray ML, Picelli G, Hsia Y, Sen FE, Giaquinto C, Ceci A, Sturkenboom M, Wong IC; TEDDY Network of Excellence. The prescribing of analgesics and non-steroidal anti-inflammatory drugs in paediatric primary care in the UK, Italy and the Netherlands. Pharmacol Res. 2010; 62(3):243-8. doi: 10.1016/j.phrs.2010.04.006. Epub 2010 May 6.
7. Sarganas G, Buttery AK, Zhuang W, Wolf IK, Grams D, Rosario AS, et al. Prevalence, trends, patterns and associations of analgesic use in Germany. BMC Pharmacol Toxicol. 2015; 16:28. doi: 10.1186/s40360-015-0028-7
8. Ajitha Sharma, Oommen Shweta. Assessment of drug prescription pattern in children: A descriptive study .National Journal of Physiology, Pharmacy and Pharmacology. 2016; 1(6):74-81
9. Sachdeo G, Keche Y, Yegnanarayan R, Sachdeo S, Sakharam C, Patankar S. Prescription analysis of drugs prescribed for children in some towns of Maharashtra. Asian J Biomed Pharm Sci. 2013; 3(21):17–9
10. Kumar MA, Ram KT, Ramasamy C. Cross sectional prospective study on drug utilization in an outpatient pediatric department of tertiary care teaching hospital. Global J Pharm. 2013; 7(2): 99–102. 18.
11. Gedam DS, Patel U, Verma M, Gedam S, Chourishi A. Drug prescription pattern in pediatric outpatient department in a teaching hospital in central India. Int J Pharm Sci Rev Res. 2012; 17(2):42–5.
12. Venkateswaramurthy N, Murali R, Kumar RS. The study of drug utilization pattern in pediatric patients. Int J Pharm Pharm Sci. 2013; 5(3):140–4.
13. Thiruthopu NS, Mateti UV, Bairi R, Sivva D, Martha S. Drug utilization pattern in South Indian pediatric population: a prospective study. Perspect Clin Res. 2014; 5(4):178–83.
2. Botzenhardt S, Rashed AN, Wong IC, Tomlin S, Neubert A. Analgesic Drug Prescription Patterns on Five International Paediatric Wards. Paediatr Drugs. 2016; 18(6):465-473.
3. Modig S, Elmståhl S.. Kidney function and use of nonsteroidal anti-inflammatory drugs among elderly people: a cross-sectional study on potential hazards for an at risk population. Int J Clin Pharm. 2018; 40(4):870-877. doi: 10.1007/s11096-018-0598-8. Epub 2018 Feb 19.
4. Valkhoff VE, Schade R, 't Jong GW, Romio S, Schuemie MJ, Arfe A, Garbe E et al. Population-based analysis of non-steroidal anti-inflammatory drug use among children in four European countries in the SOS project: what size of data platforms and which study designs do we need to assess safety issues? BMC Pediatr. 2013; 13:192. doi: 10.1186/1471-2431-13-192.
5. Rashed AN, Wong IC, Wilton L, Tomlin S, Neubert A. Drug Utilisation Patterns in Children Admitted to a Paediatric General Medical Ward in Five Countries.Drugs Real World Outcomes. 2015; 2(4):397-410. Epub 2015 Nov 18
6. Neubert A, Verhamme K, Murray ML, Picelli G, Hsia Y, Sen FE, Giaquinto C, Ceci A, Sturkenboom M, Wong IC; TEDDY Network of Excellence. The prescribing of analgesics and non-steroidal anti-inflammatory drugs in paediatric primary care in the UK, Italy and the Netherlands. Pharmacol Res. 2010; 62(3):243-8. doi: 10.1016/j.phrs.2010.04.006. Epub 2010 May 6.
7. Sarganas G, Buttery AK, Zhuang W, Wolf IK, Grams D, Rosario AS, et al. Prevalence, trends, patterns and associations of analgesic use in Germany. BMC Pharmacol Toxicol. 2015; 16:28. doi: 10.1186/s40360-015-0028-7
8. Ajitha Sharma, Oommen Shweta. Assessment of drug prescription pattern in children: A descriptive study .National Journal of Physiology, Pharmacy and Pharmacology. 2016; 1(6):74-81
9. Sachdeo G, Keche Y, Yegnanarayan R, Sachdeo S, Sakharam C, Patankar S. Prescription analysis of drugs prescribed for children in some towns of Maharashtra. Asian J Biomed Pharm Sci. 2013; 3(21):17–9
10. Kumar MA, Ram KT, Ramasamy C. Cross sectional prospective study on drug utilization in an outpatient pediatric department of tertiary care teaching hospital. Global J Pharm. 2013; 7(2): 99–102. 18.
11. Gedam DS, Patel U, Verma M, Gedam S, Chourishi A. Drug prescription pattern in pediatric outpatient department in a teaching hospital in central India. Int J Pharm Sci Rev Res. 2012; 17(2):42–5.
12. Venkateswaramurthy N, Murali R, Kumar RS. The study of drug utilization pattern in pediatric patients. Int J Pharm Pharm Sci. 2013; 5(3):140–4.
13. Thiruthopu NS, Mateti UV, Bairi R, Sivva D, Martha S. Drug utilization pattern in South Indian pediatric population: a prospective study. Perspect Clin Res. 2014; 5(4):178–83.
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Puja D, Dhasmana D, Kohli S, Chander V. Pattern of analgesic use in hospitalized children at a pediatric general ward in a tertiary care teaching hospital. JDDT [Internet]. 15Jan.2019 [cited 9Jul.2020];9(1):199-01. Available from: http://jddtonline.info/index.php/jddt/article/view/2215
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