Muco-constriction: A ray of promise from medicinal plants

  • V Aruna Dr. JRK’s Research & Pharmaceuticals Pvt. Ltd., No.18 & 19, Perumal Koil Street, Kunrathur, Chennai- 600069
  • R Soundharya Dr. JRK’s Research & Pharmaceuticals Pvt. Ltd., No.18 & 19, Perumal Koil Street, Kunrathur, Chennai- 600069
  • GV Amruthavalli Dr. JRK’s Research & Pharmaceuticals Pvt. Ltd., No.18 & 19, Perumal Koil Street, Kunrathur, Chennai- 600069
  • R Gayathri Dr. JRK’s Research & Pharmaceuticals Pvt. Ltd., No.18 & 19, Perumal Koil Street, Kunrathur, Chennai- 600069

Abstract

JRK’s Anti-coff was evaluated for blood purification benefit by phagocytosis.  and surprisingly we found that Aniscochilus carnosus showed muco-constriction benefit, while Ocimum sanctum and Adathoda vasica showed mucolytic property. The clinical implication of the above therapeutic benefits is discussed in detail in the article from the context of Siddha system of medicine. The findings are discussed in the article.


Keywords: Mucolytic, Anti-coff, Cough, N-acetyl cysteine, Xylometazoline

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Author Biographies

V Aruna, Dr. JRK’s Research & Pharmaceuticals Pvt. Ltd., No.18 & 19, Perumal Koil Street, Kunrathur, Chennai- 600069

Dr. JRK’s Research & Pharmaceuticals Pvt. Ltd., No.18 & 19, Perumal Koil Street, Kunrathur, Chennai- 600069

R Soundharya, Dr. JRK’s Research & Pharmaceuticals Pvt. Ltd., No.18 & 19, Perumal Koil Street, Kunrathur, Chennai- 600069

Dr. JRK’s Research & Pharmaceuticals Pvt. Ltd., No.18 & 19, Perumal Koil Street, Kunrathur, Chennai- 600069

GV Amruthavalli, Dr. JRK’s Research & Pharmaceuticals Pvt. Ltd., No.18 & 19, Perumal Koil Street, Kunrathur, Chennai- 600069

Dr. JRK’s Research & Pharmaceuticals Pvt. Ltd., No.18 & 19, Perumal Koil Street, Kunrathur, Chennai- 600069

R Gayathri, Dr. JRK’s Research & Pharmaceuticals Pvt. Ltd., No.18 & 19, Perumal Koil Street, Kunrathur, Chennai- 600069

Dr. JRK’s Research & Pharmaceuticals Pvt. Ltd., No.18 & 19, Perumal Koil Street, Kunrathur, Chennai- 600069

References

1. Amruthavalli GV et al, “Blood Purification an Essential Strategy for Cough Management ". Journal of AYUSH. (INPRESS)
2. Cazzola M, Rogliani P, Calzetta L, Hanania NA, Matera MG. Impact of Mucolytic Agents on COPD Exacerbations: A Pair-wise and Network Meta-analysis. COPD. 2017; 14(5):552-563. doi: 10.1080/15412555.2017.1347918. Epub 2017 Jul 28.
3. D A Deswati, M A Dhina and S R Mubaroq. Mucolytic Activity Test of Shallot Extract (Allium Ascalonicum L) by in Vitro. IOP Conf. Series: Materials Science and Engineering 2018; 288:012141 doi:10.1088/1757-899X/288/1/012141
4. Marion Richardson et.al, The physiology of mucus and sputum production in the respiratory system. Respiratory. Vol: 99, Issue: 23, Page No: 63
5. Knowles MR, Boucher RC. Mucus clearance as a primary innate defense mechanism for mammalian airways. J Clin Invest. 2002; 109:571–577.
6. Davis CW, Dickey BF. Regulated airway goblet cell mucin secretion. Annu Rev Physiol. 2008; 70:487–512. [PubMed] Up-to-date review of the composition, function, and regulation of the airway secretory cell exocytic machinery
7. Jun-Sung Han, Sang-Hi Park, Young Duck Shin et. al., The effect of Xylometazoline spray for expansion of nasal cavity. Korean J Anesthesiol. 2013; 65(2):132–135
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How to Cite
Aruna, V., Soundharya, R., Amruthavalli, G., & Gayathri, R. (2019). Muco-constriction: A ray of promise from medicinal plants. Journal of Drug Delivery and Therapeutics, 9(1), 180-182. https://doi.org/10.22270/jddt.v9i1.2206