Phytochemical analysis, antioxidant, antidiabetic and anti-inflammatory activity of bark of Gardenia latifolia

  • Farheen Ansari Technocrats Institute of Technology- Pharmacy, Bhopal (M. P.), India
  • Salaj Khare Technocrats Institute of Technology- Pharmacy, Bhopal (M. P.), India
  • B. K. Dubey Technocrats Institute of Technology- Pharmacy, Bhopal (M. P.), India
  • Amit Joshi Technocrats Institute of Technology- Pharmacy, Bhopal (M. P.), India
  • Amit Jain Technocrats Institute of Technology- Pharmacy, Bhopal (M. P.), India
  • Suresh Dhakad Technocrats Institute of Technology- Pharmacy, Bhopal (M. P.), India

Abstract

Gardenia latifolia (Rubiaceae) is commonly known as Indian boxwood or Ceylon boxwood, is a densely foliaceous small tree that occurs throughout the greater parts of Indian common in deciduous forests along the streams. The stem bark and fruits are reported to be used in the treatment of various ailments such as snake bite, skin diseases, stomach pains, caries in humans and ephemeral fever in live stocks. Many beneficial medicinal products are used to treat various serious diseases and disorders like diabetes, cancer and cardiovascular diseases without side effects. Hence our study focused to investigate the phytochemical analysis, quantification of bioactive compounds, in vitro free radical scavenging activity (DPPH radical method), anti-inflammatory activity (Carrageenan induced hind paw oedema ), in vitro anti-diabetic activity by enzyme inhibition activity of bark of Gardenia latifolia (hydroalcoholic extract) which has boundless medicinal properties. The results of this study showed the evidence that the extracts when tested for their phytochemicals and free radical scavenging activity were found to have considerable antioxidant potential. This plant also exhibit better in vitro enzyme inhibitory activity and anti-inflammatory activity. The results of this study indicate that the hydroalcoholic extract of Gardenia latifolia bark has significant pharmacological properties.


Keywords: Gardenia latifolia, Phytochemical analysis, DPPH radical method, Anti-inflammatory activity, Anti-diabetic activity

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Author Biographies

Farheen Ansari, Technocrats Institute of Technology- Pharmacy, Bhopal (M. P.), India

Technocrats Institute of Technology- Pharmacy, Bhopal (M. P.), India

Salaj Khare, Technocrats Institute of Technology- Pharmacy, Bhopal (M. P.), India

Technocrats Institute of Technology- Pharmacy, Bhopal (M. P.), India

B. K. Dubey, Technocrats Institute of Technology- Pharmacy, Bhopal (M. P.), India

Technocrats Institute of Technology- Pharmacy, Bhopal (M. P.), India

Amit Joshi, Technocrats Institute of Technology- Pharmacy, Bhopal (M. P.), India

Technocrats Institute of Technology- Pharmacy, Bhopal (M. P.), India

Amit Jain, Technocrats Institute of Technology- Pharmacy, Bhopal (M. P.), India

Technocrats Institute of Technology- Pharmacy, Bhopal (M. P.), India

Suresh Dhakad, Technocrats Institute of Technology- Pharmacy, Bhopal (M. P.), India

Technocrats Institute of Technology- Pharmacy, Bhopal (M. P.), India

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How to Cite
Ansari, F., Khare, S., Dubey, B. K., Joshi, A., Jain, A., & Dhakad, S. (2019). Phytochemical analysis, antioxidant, antidiabetic and anti-inflammatory activity of bark of Gardenia latifolia. Journal of Drug Delivery and Therapeutics, 9(1), 141-145. https://doi.org/10.22270/jddt.v9i1.2196