Unani Perspective and New Researches of Sa’ad ku’fi (Cyperus rotundus): A Review

  • Hana Abbasi P.G. Scholar, Assistant Professor, Deptt. Of Ilmul Advia, School of Unani Medical Education and research, Jamia Hamdard, New Delhi, 110062
  • Hifzul Kabir P.G. Scholar, Assistant Professor, Deptt. Of Ilmul Advia, School of Unani Medical Education and research, Jamia Hamdard, New Delhi, 110062


Cyperus rotundus L. (cyperaceae) is an important medicinal plant which is used in traditional medicine particularly in Unani system of medicine. It is commonly known as motha which is a lawn grass and grows easily in tropical, subtropical and temperate regions. Major Chemical constituents enclosed with this herb are flavonoids, tannins, glycosides, furochromones, monoterpenes, sesquiterpenes, sitosterol, alkaloids, saponins, terpenoids, essential oils, starch, carbohydrates, protein, separated amino acids and many other secondary metabolites. Different parts of cyperus rotundus have been reported to possess multiple pharmacological actions like antibacterial, anticancerous, anticonvulsant, antidiabetic, antidiarrheal, antigenotoxic, anti-inflammatory, antilipidemic, antimalarial, antimutagenic, antiobesity, antioxidant, anti-uropathogenic, hepatoprotective, cardioprotective, neuroprotective, and nootropic agent.

Keywords: Unani, sa’ad, flavonoids, sesquiterpenes, antibacterial, antilipidemic.


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Author Biographies

Hana Abbasi, P.G. Scholar, Assistant Professor, Deptt. Of Ilmul Advia, School of Unani Medical Education and research, Jamia Hamdard, New Delhi, 110062

P.G. Scholar, Assistant Professor, Deptt. Of Ilmul Advia, School of Unani Medical Education     and research, Jamia Hamdard, New Delhi, 110062

Hifzul Kabir, P.G. Scholar, Assistant Professor, Deptt. Of Ilmul Advia, School of Unani Medical Education and research, Jamia Hamdard, New Delhi, 110062

P.G. Scholar, Assistant Professor, Deptt. Of Ilmul Advia, School of Unani Medical Education     and research, Jamia Hamdard, New Delhi, 110062


1. Dang GK, Parekar RR, Kamat SK, Scindia AM, Rege NN, Antiinflammatory activity of Phyllanthus emblica, Plumbago zeylanica and Cyperus rotundus in acute models of inflammation, Phytother Res, 2011; 25(6):904-8.
2. Gupta MB, Palit TK, Singh N, Bhargava KP, Pharmacological studies to isolate the active constituents from Cyperus rotundus possessing anti- inflammatory, anti-pyretic and analgesic activities, Indian Journal of Medical Research, 1971; 59:76–82.
3. Nima ZA, Jabier MS, Wagi RI, Hussain HA, Extraction, identification and antibacterial activity of Cyperus oil from Iraqi C. rotundus, Eng.& Technology, 2008; 26:10,
4. Uddin SJ, Mondal K, Shilpi JA, Rahnan MT, Antidiarrhoeal activity of Cyperus rotundus, Fitoterapia, 2006; 77 (2):134–13.
5. Won-Gil Seo, Hyun-Ock Pae, Gi-Su Oh, Kyu-Yun Chai, Tae-Oh Kwon, Young-Gab Yun, Na-Young Kim, Hun-Taeg Chung, Inhibitory effects of methanol extract of Cyperus rotundus rhizomes on nitric oxide and superoxide productions by murine macrophage cell line, RAW 264.7 cells, Journal of Ethnopharmacology, 2001; 76(1): 59– 64.
6. Yu J., Lei G., Cai L. and Zou Y, Chemical composition of C. rotundus extract, J. Phytochemistry, 2004; 65: 881-89.
7. Classification of Cyperus rotundus L. United State Department of Agriculture. Available from: http://www.plants.usda.gov/java/ Classification. [Last cited on 2013 Apr 10].
8. Kirtikar K.R. and Basu B.D, Indian Medicinal Plants, Valley Offset Printers and Publishers Dehradun, 1996; 4:2638-2640.
9. Hashmat Imam, et.al, The incredible benefits of Nagarmotha (Cyperus rotundus), International Journal of Nutrition, Pharmacology, Neurological Diseases, 2017; 4(1): 23-26.
10. Jain p.k., et.al, Ethnopharmacological study of cyperus rotundus - a herb used by tribal community as a traditional medicine for treating various diseases, Innov J Ayruvedic Sciences, 2016; 4(1):1-4.
11. Parotta JA, Healing Plants of Peninsular India.,New York, CABI Publishing, 2001; 2‑66.
12. Swarbrick JT, Weeds of the Pacific Islands, Technical Paper No.209. Noumea, New Caledonia, South Pacific Commission, 1997; 124.
13. Ali Esmail Al-Snafi, A review on Cyperus rotundus A potential medicinal plant, IOSR Journal Of Pharmacy, 2016; 6(7):32-48.
14. Stone B, The flora of Guam, Micronesica, 1970; 6:167.
15. Wills GD, Description of purple and yellow nutsedge (Cyperus rotundus and C. esculentus), Weed Technology, 1987; 1:2-9.
16. Gani M.N, Khazainul Advia, Aijaz Publishing House, New Delhi, 2:803-805.
17. Hakeem M.A, Bustan ul Mufridaat, zafar book depot,New Delhi, 1999, p.p 150.
18. Kabiruddin, mukhzinul Mufridat, Sheikh Mohd Basheer Industries, Urdu Bazaar, Lahore, 1996; 566.
19. Khan M.A, Muheet e Azam(urdu translation), CCRUM, New Delhi, 2014; 3:95-97.
20. Bisht A, Bisht GR, Singh M, Gupta R, Singh V, Chemical composition and antimicrobial activity of essential oil of tubers of Cyperus rotundus Linn collected from Dehradun (Uttarakhand), Int J Res Pharm Biomed Sci, 2011; 661‑5.
21. Dhilon RS, Singh S, Kundra S, Basra AS, , Studies on the chemical composition and biological activity of essential oil from Cyperus rotundus Linn, Plant Growth Regul, 1993; 13(1):89-93.
22. Hikino H, Suzuki N, Takemoto T. Structure and absolute configuration of kusunol. Chem Pharm Bull (Tokyo), 1968; 16(5):832-8.
23. Kalsi PS, Sharma A, Singh A, Singh IP, Chabra BR., Biogenetically important sesquiterpenes from Cyperus rotundus, Fitoterapia, 1995; 66(1):94.
24. Kapadia VH, Naik VG, Wadia MS, Dev S, Sesquiterpenoids from the essential oil of Cyperim wtundus. Tetrahedron Lett , 1967; 4661.
25. Meena A.K., Review on Cyperus rotundus - A Potential Herb, International Journal of Pharmaceutical and Clinical Research, 2010; 2(1):20-22.
26. Visetson S, Milne M, Milne J, Toxicity of 4, 11‑Selinnadien‑3‑one from nutsedge (Cyperus rotundus L.) tuber extracts to diamondback moth larvae (Plutella xylostella L.), detoxification mechanisms and toxicity to non target species, Kasetsart J Nat Sci, 2001; 35:284‑92.
27. Chandratre R. S., Chandarana S, Mengi S. A., Effect of Aqueous Extract of Cyperus rotundus on Hyperlipidaemia in Rat Model., International Journal of Pharmaceutical & Biological Archives, 2012; 3(3):598-600.
28. Lemaure B, Touché A, Zbinden I, Moulin J, Courtois D, Macé K and Darimont C, , Administration of Cyperus rotundus tubers extract prevents weight gain in obese Zucker rats. Phytother Res, 2007; 21:724- 730.
29. Nagulendran K R, Mahesh R and Begum V H, , Preventive role of Cyperus rotundus rhizomes extract on age associated changes in glucose and lipids, Pharmacologyonline, 2007; 2:318-325.
30. Kilani S. et.al., , In vitro evaluation of antibacterial, antioxidant, cytotoxic and apoptotic activities of the tubers infusion and extracts of Cyperus rotundus, Bioresource Technology, 2008; 9004–9008.
31. Kumar K.H.et.al., Phytochemical analysis and biological properties of Cyperus rotundus L., Industrial Crops and Products, 2014; 52:815–826.
32. Malekian, N., Rabbani, M., Ghannadi, A, Evaluation of the effect of Cyperus rotundus L. in scopolamine-induced learning deficit in mice. Research in Pharmaceutical Sciences, 2012; 7(5):834.
33. Mehdi Mehdizadeh, , Protective Effects of Cyperus Rotun- dus Extract on Amyloid β-Peptide (1-40)-Induced Memory Impairment in Male Rats: A Behavioral Study, Basic and Clinical Neuroscience, 2017; 8:249-254.
34. Soleimani Asl, S., Mousavizedeh, K., Pourheydar, B., Soleimani, M., Rahbar, E., & Mehdizadeh M, , Protective effects of N-acetylcysteine on 3, 4-methylene dioxymethamphetamine- induced neurotoxicity in male Sprague–Dawley rats. Metabolic Brain Disease, 2013; 28(4):677–686.
35. Chandratre RS, Chandarana S and Mengi SA, Lipid lowering activity of alcoholic extract of Cyperus rotundus. IJRPC, 2011; 1(4):1042- 1045.
36. Parekh J. and Chanda S, In-vitro Antimicrobial Activities of Extractsof Launaea procumbens Roxb. (Labiateae), Vitis vinifera L. (Vitaceae) and Cyperus rotundus L. (Cyperaceae) African Journal of Biomedical Research, 2006; 9(2):89-93.
37. Puratchikody A, Devi Nithya C, Nagalakshmi G, Wound healing activity of cyperus rotundus linn. Indian journal of pharmaceutical sciences, 2006; 68:97-101.
38. El-Gohary HMA, Study of essential oils of the tubers of Cyperus rotuntdus L and Cyperus alopecuroides ROTTB, Bull Fac Pharm Cairo Univ, 2004; 42(1):157-164.
39. Sharma SK and Singh AP, Antimicrobial investigations on rhizomes of Cyperus rotundus Linn. Der Pharmacia Lettre, 2011; 3(3):427-431.
40. Sri Ranjani Sivapalan, Medicinal uses and Pharmacological activities of Cyperus rotundus Linn – A Review, International Journal of Scientific and Research Publications, 2013; 3(5):1-7.
41. Kempraj V, Bhat SK, Ovicidal and larvicidal activities of Cyperus giganteus Vahl and Cyperus rotundus Linn. essential oils against Aedes albopictus (Skuse)Nat Prod Radiance, 2008; 7:416‑9.
42. Singh SP, Raghavendra K and Dash AP, Evaluation of hexane extract of tuber of root of Cyperus rotundus Linn (Cyperaceae) for repellency against mosquito vectors, J Parasitol Res, 2009; 1:1-5.
43. Solita ES and Castor L, Phytochemical and pesticidal properties of barsanga (Cyperus rotundus Linn.), JPAIR Multidiscip J, 2011; 6:197-214.
44. Al-Snafi AE, Al-Trikrity AH. and Ahmad RH, Hypoglycemic effect of Teucrium polium and Cyperus rotundus in normal and diabetic rabbits. Med J Tikrit Univ 2013; 9(2):1-10.
45. Raut NA and Gaikwad NJ, Antidiabetic activity of hydro-ethanolic extract of Cyperus rotundus in alloxan induced diabetes in rats, Fitoterapia, 2006; 77:585-588.
46. Singh Pradeep, Khosa Ratan L.et.al., Antidiabetic activity of ethanolic extract of Cyperus rotundus rhizomes in streptozotocin-induced diabetic mice, Journal of Pharmacy & Bioallied Sciences, 2015; 7(4):289–292.
47. Hema, N., Avadhani, R., Ravishankar, B., Anupama, A comparative analysis of antioxidant potentials of aqueous and ethanolic extracts of Cyperus rotundus (L.). Asian J. Biomed. Pharm. Sci, 2013; 3:7–11.
48. Nagulendran kr, Velavan S, Mahesh R, In Vitro Antioxidant Activity and Total Polyphenolic Content of Cyperus rotundus Rhizomes, E-Journal of Chemistry, 2007; 4(3):440-449.
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Abbasi H, Kabir H. Unani Perspective and New Researches of Sa’ad ku’fi (Cyperus rotundus): A Review. JDDT [Internet]. 15Nov.2018 [cited 30May2020];8(6):378-81. Available from: http://jddtonline.info/index.php/jddt/article/view/2059