Electronic delivery of nicotine: help in smoking cessation or an alternative means of addiction

  • Bhupinder Bhyan Department of Pharmaceutics, NIMS Institute of Pharmacy, NIMS University, Jaipur (Raj.) 303121, India.
  • sarita Jangra Department of Pharmacy Practice, NIMS Institute of Pharmacy, NIMS University, Jaipur (Raj.) 303121, India.

Abstract

All over the world currently there are billions of people who use tobacco regularly that’s why now these days the tobacco is one of the most widely used drug. Many of scientific evidences reveal that tobacco is dangerous to human health. Tobacco contains plethora of harmful chemical substances, out of which many of them are carcinogens. Smoking is responsible for 90% of all lung cancer and mouth cancer, 75% of chronic bronchitis and emphysema and 25 % of ischemic heart disease cases so tobacco is one of the leading preventable causes of deaths. In consideration of all these factors this review discusses various aspects of these electronic cigarettes like their structural components, working mechanism and their role in smoking cessation. E-cigarettes now gained a lot of popularity. This review also helps to aware health care professionals along with general population about the safety, myths, future challenges and about all pros and cons of using E-cigarettes.


Keywords: Cigarettes, electronic cigarettes, e-cigarettes, nicotine, public health, smoking cessation, tobacco

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Author Biographies

Bhupinder Bhyan, Department of Pharmaceutics, NIMS Institute of Pharmacy, NIMS University, Jaipur (Raj.) 303121, India.

Department of Pharmaceutics, NIMS Institute of Pharmacy, NIMS University, Jaipur (Raj.) 303121, India.

sarita Jangra, Department of Pharmacy Practice, NIMS Institute of Pharmacy, NIMS University, Jaipur (Raj.) 303121, India.

Department of Pharmacy Practice, NIMS Institute of Pharmacy, NIMS University, Jaipur (Raj.) 303121, India.

References

1. Shaik B, Tepoju M. A cross sectional community based study on the prevalence of tobacco smoking (considering only cigarette and hookah smoking) among the urban youth. AP J Psychol Med 2013; 14:164-70.
2. Prabhat J, Richard P. Global Effects of Smoking, of Quitting, and of Taxing Tobacco. N Engl J Med 2014; 370:60-8.
3. Zhu SH, Sun JY, Bonnevie E. Four hundred and sixty brands of e-cigarettes and counting: implications for product regulation. Tob Control 2014; 23:3–9.
4. Farsalinos K, Romagna G, Tsiapras D. Impact of flavour variability on electronic cigarette use experience: an internet survey. Int J Environ Res Public Health 2013; 10:7272–7282.
5. Goniewicz ML, Kuma T, Gawron M et al. Nicotine levels in electronic cigarettes. Nicotine & Tobacco Research 2013; 15:158–166.
6. Goniewicz ML, Hajek P & McRobbie H. Nicotine content of electronic cigarettes, its release in vapour and its consistency across batches: regulatory implications. Addiction 2014; 109:500–507.
7. Orr KK, Asal NJ. Efficacy of electronic cigarettes for smoking cessation. Annals of Pharmacotherapy 2014; 48:1502–1506.
8. Adriaens K, Van Gucht D, Declerck P et al. Effectiveness of the electronic cigarette: an eight-week Flemish study with six-month follow-up on smoking reduction, craving and experienced benefits and complaints. Int J Environ Res Public Health 2014; 11:11220–11248.
9. Farsalinos K, Romagna G, Tsiapras D et al. Evaluation of electronic cigarette use (vaping) topography and estimation of liquid consumption: implications for research protocol standards definition and for public health authorities’ regulation. Int J Environ Res Public Health 2013; 10:2500–2514.
10. McRobbie H, Bullen C, Hartmann-Boyce J et al. Electronic cigarettes for smoking cessation and reduction. Cochrane Database of Systematic Reviews 2014; 12:102-116.
11. Cahill K, Stead L. Lancaster T. Nicotine receptor partial agonists for smoking cessation. Cochrane Database of Systematic Reviews 2012; 4:61:73.
12. Stead L, Perera R, Bullen C et al. Nicotine replacement therapy for smoking cessation. Cochrane Database of Systematic Reviews 2012; 14(11):CD000146.
13. National Institute for Clinical Excellence (NICE) Tobacco: harm-reduction approaches to smoking (2013). London: NICE. Available from: https://www.nice.org.uk/guidance/ph45 (accessed 1 December 2015).
14. Etter JF. Electronic cigarettes: a survey of users. BMC Public Health 2010; 10:231.
15. Pepper JK & Brewer NT. Electronic nicotine delivery system (electronic cigarette) awareness, use, reactions and beliefs: a systematic review. Tob Control 2014; 23(5):375–384.
16. Vansickel AR, Eissenberg T. Electronic cigarettes: effective nicotine delivery after acute administration. Nicotine & Tobacco Research 2013; 15:267–270.
17. Bullen C, McRobbie H, Thornley S et al. Effect of an electronic nicotine delivery device (e-cigarette) on desire to smoke and withdrawal, user preferences and nicotine delivery: randomised cross-over trial.Tob Control 2010; 19:98–103.
18. Dawkins L, Turner J, Hasna S et al. The electronic-cigarette: effects on desire to smoke, withdrawal symptoms and cognition. Addict Behav 2012; 37:970–973.
19. Etter JF, Bullen C. Electronic cigarette: users profile, utilization, satisfaction and perceived efficacy.Addiction 2011; 106:2017–2028.
20. Vansickel AR, Cobb CO, Weaver MF et al. A clinical laboratory model for evaluating the acute effects of electronic “cigarettes”: nicotine delivery profile and cardiovascular and subjective effects.Cancer Epidemiology, Biomarkers & Prevention 2010; 19(8):1945–1953.
21. Vansickel AR, Weaver MF & Eissenberg T. Clinical laboratory assessment of the abuse liability of an electronic cigarette. Addiction 2012; 107(8):1493–1500.
22. Polosa R, Caponnetto P, Morjaria JB et al. Effect of an electronic nicotine delivery device (e-cigarette) on smoking reduction and cessation: a prospective 6-month pilot study. BMC Public Health2011; 11:786.
23. Siegel MB, Tanwar KL, Wood KS. Electronic cigarettes as a smoking-cessation: tool results from an online survey. American Journal of Preventive Medicine 2011; 40:472–475.
24. Bullen C, Howe C, Laugesen M et al. Electronic cigarettes for smoking cessation: a randomised controlled trial. Lancet 2013; 382:1629–1637.
25. Foulds J, Veldheer S, Berg A. Electronic cigarettes (e-cigs): views of aficionados and clinical/public health perspectives. Int J Clin Pract 2011; 65:1037–1042.
26. Jensen RP, Luo W, Pankow JF et al. Hidden formaldehyde in e-cigarette aerosols. N Engl J Med 2015; 372:392–394.
27. Public Health England. E-cigarettes: An evidence update (2015). London: Public Health England. Available from: www.gov.uk/government/publications/e-cigarettes-an-evidence-update
28. Konstantinos E. Farsalinos and Riccardo Polosa Safety evaluation and risk assessment of electronic cigarettes as tobacco cigarette substitutes: a systematic review, Therapeutic Advances in Drug Safety 2015; 5:67-87.
29. Etter JF, Bullen C. Saliva cotinine levels in users of electronic cigarettes. European Respiratory Journal 2011; 38:1219–1220.
30. Nutt DJ, Phillips LD, Balfour D et al. Estimating the harms of nicotine-containing products using the MCDA approach. European Addiction Research 2014; 20:218–225.
31. American Lung Association statement on e-cigarettes. ALA website. lung.org/our-initiatives/tobacco/oversight-and-regulation/statement-on-e-cigarettes.html. Updated March 2015. Accessed December 17, 2016.
32. Drug facts: electronic cigarettes (e-cigarettes). National Institute on Drug Abuse website. drugabuse.gov/sites/default/files/drugfacts_e-cigs_9_15.pdf. Published August 2015. Updated August 2015. Accessed October 18, 2015.
33. Summary of results: laboratory analysis of electronic cigarettes conducted by FDA. FDA website. www.fda.gov/NewsEvents/PublicHealthFocus/ucm173146.htm. Updated April 22, 2014. Accessed October 20, 2016.
34. Myths and facts about E-cigarette. American Lung Association website. lung.org/stop-smoking/smoking-facts/myths-and-facts-about-e-cigs.html. Accessed September 17, 2016.
35. Barrington-Trimis JL, Samet JM, McConnell R. Flavorings in electronic cigarettes: an unrecognized respiratory health hazard? JAMA. 2014; 312(23):2493-2494.
36. E-cigarette use among non-cigarette smoking youth triples [press release]. Washington, DC: American Lung Association; August 25, 2014 lung.org/about-us/media/press-releases/e-cigarette-use-triples-in-nonsmokinr-youth.html. Accessed September 17, 2016.
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How to Cite
Bhyan, B., & Jangra, sarita. (2018). Electronic delivery of nicotine: help in smoking cessation or an alternative means of addiction. Journal of Drug Delivery and Therapeutics, 8(6), 356-359. https://doi.org/10.22270/jddt.v8i6.2045