DEVELOPMENT OF NANOCRYSTAL FORMULATION WITH IMPROVED DISSOLUTION

  • Jaspreet Kaur Saini Department of Pharmaceutics, ASBASJSM College of Pharmacy, Bela (Roper), Punjab, India
  • Sandeep Kumar Department of Pharmaceutics, ASBASJSM College of Pharmacy, Bela (Roper), Punjab, India

Abstract

With the advancement in modern pharmaceutical technologies, Nanotechnology is the one of the most establish technology which is used to improve the therapeutic index and to overcome the formulation challenges of poorly water-soluble compounds. Nanocrystals, in nano range, is the interesting approach for poorly soluble drugs. Due to the small size, increased surface area enhanced the dissolution rate and solubility of drug. In this paper, current technologies and methods in nanocrystal preparation, stabilization, pharmaceutical applications and limitations of nanocrystal are reviewed.


Keywords: Nanocrystal, limitations, stabilization, preparation, applications

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Author Biographies

Jaspreet Kaur Saini, Department of Pharmaceutics, ASBASJSM College of Pharmacy, Bela (Roper), Punjab, India

Department of Pharmaceutics, ASBASJSM College of Pharmacy, Bela (Roper), Punjab, India

Sandeep Kumar, Department of Pharmaceutics, ASBASJSM College of Pharmacy, Bela (Roper), Punjab, India

Department of Pharmaceutics, ASBASJSM College of Pharmacy, Bela (Roper), Punjab, India

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How to Cite
Saini, J., & Kumar, S. (2018). DEVELOPMENT OF NANOCRYSTAL FORMULATION WITH IMPROVED DISSOLUTION. Journal of Drug Delivery and Therapeutics, 8(5), 118-129. https://doi.org/10.22270/jddt.v8i5.1946