IN-VITRO AND IN VIVO STUDIES OF CETUXIMAB LOADED POLYMERIC NANOPARTICLES

  • Ajinder Kaushik College of Pharmacy, Sri Satya Sai University of Technology & Medical Sciences, Pachama, Sehore (M.P.) 466001
  • Hemant Kumar Sharma College of Pharmacy, Sri Satya Sai University of Technology & Medical Sciences, Pachama, Sehore (M.P.) 466001

Abstract

Nanoparticles speak to one of the appealing choices in the compelling treatment of tumor chemo-treatment. In the present work, definition and improvement of a novel Cetuximab (MTX)- stacked biodegradable nanoparticles utilizing poly(D,L-lactide-co-glycolide) (PLGA) was done. The arranged nanoparticles were assessed for physicochemical properties, for example, molecule measure, zeta potential, discharge thinks about, and so forth. Molecule size of upgraded definition was < 200 nm. Our essential outcomes exhibit that the created Cetuximab-stacked PLGA nanoparticles discharging the medication for delayed timeframe.


Keywords: Cetuximab; PLGA 50:50; nanoparticles

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Author Biographies

Ajinder Kaushik, College of Pharmacy, Sri Satya Sai University of Technology & Medical Sciences, Pachama, Sehore (M.P.) 466001

College of Pharmacy, Sri Satya Sai University of Technology & Medical Sciences, Pachama, Sehore (M.P.) 466001

Hemant Kumar Sharma, College of Pharmacy, Sri Satya Sai University of Technology & Medical Sciences, Pachama, Sehore (M.P.) 466001

College of Pharmacy, Sri Satya Sai University of Technology & Medical Sciences, Pachama, Sehore (M.P.) 466001

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How to Cite
Kaushik, A., & Sharma, H. K. (2018). IN-VITRO AND IN VIVO STUDIES OF CETUXIMAB LOADED POLYMERIC NANOPARTICLES. Journal of Drug Delivery and Therapeutics, 8(5-s), 184-188. https://doi.org/10.22270/jddt.v8i5-s.1941
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Research