• Bhagat Singh Jaiswal SOS in Pharmaceutical Sciences, Jiwaji University, Gwalior, M.P., India
  • Mukul Tailang SOS in Pharmaceutical Sciences, Jiwaji University, Gwalior, M.P., India


Argyreia speciosa (Linn.f.) (Family: Convolvulaceae, Synonyms: Argyreia nervosa) is used in the traditional Ayurvedic systems of medicine as well as in local health folklore. It is commonly known as Vidhaara in Hindi and Hawaiian Baby Woodrose and Elephant creeper in English. It is the large climber and seen throughout India up to an altitude of 500 m. A. speciosa possess various pharmacological activity such as anti-aging, gastroprotective, analgesic & anti-inflammatory, aphrodisiac, antiviral, antidiabetic,  anticonvulsion, antioxidant, antidiarrheal, antiulcer, central nervous system depressant, nematocides, nootropic, anticancer and many more. Apart from this numerous phytoconstituents have been isolated from A. speciosa. Its seeds principally contain lysergamides, eragine and isoeragine which responsible for its hallucinogenic properties. The present paper efforts bring to light the available literature on A. speciosa with respect to traditional, ethnobotanical, phytoconstituents and review of different pharmacological activities.

Keywords: Argyreia speciosa, Vidhaara, Anti-aging, Hallucinogen, Ethnobotanical


Download data is not yet available.

Author Biographies

Bhagat Singh Jaiswal, SOS in Pharmaceutical Sciences, Jiwaji University, Gwalior, M.P., India

SOS in Pharmaceutical Sciences, Jiwaji University, Gwalior, M.P., India

Mukul Tailang, SOS in Pharmaceutical Sciences, Jiwaji University, Gwalior, M.P., India

SOS in Pharmaceutical Sciences, Jiwaji University, Gwalior, M.P., India


1. Aiyer KN, Kolammal M, Pharamacognosy of ayurvedic drugs (kerala), Journal of pharmacy and pharmacology, 1964; 16(12):836.
2. Ashutosh M, Kumar AA, Ranjan PA, A literature review on Argyreia nervosa (burm. F.) Bojer, International Journal of Research in Ayurveda and Pharmacy, 2011; 2:1501-1504.
3. Wealth of India-Raw materials. New Delhi: Publication and information directorate, CSIR; 1985. P. 418.
4. Nadkarni AK. Indian Materia Medica. Bombay: Popular parkashan private Ltd; 2007. P. 137.
5. Girach RD, Aminuddin, Ahmad M, Medical ethnobotany of sundargarh, Orissa, India, Pharmaceutical Biology, 1998; 36:20-24.
6. Borsutzky M, Passie T, Paetzold W, Emrich HM and Schneider U, Hawaiian baby wood rose, (Psycho-) Pharmacological effects of the seeds of Argyreia nervosa, A case-oriented demonstration, Der Nervenarzt, 2002; 73:892-896.
7. Husain OPA, Viramani SP, Popli LN, Misra MM, Gupta GN, Srivastava Z, Singh AK. Dictionary of Indian Medicinal Plants. Lucknow: Central Institute of Medicinal and Aromatic Plants; 1992. P. 45-46.
8. Angelis Lde, 5-HT2A antagonists in psychiatric disorders, Current Opinion in Investigational Drugs, 2002; 3:106-112.
9. Joseph A, Mathew S, Skaria BP, Sheeja EC, Medicinal uses and biological activities of Argyreia speciosa sweet (Hawaiian baby woodrose) - an overview, Indian Journal of Natural Products and Resources, 2011; 2:286-291.
10. Paulke A, Kremer C, Wunder C, Achenbach J, Djahanschiri B. Argyreia nervosa (Burm. f.): receptor profiling of lysergic acid amide and other potential psychedelic LSD-like compounds by computational and binding assay approaches. J Ethnopharmacol. 2013; 148:492-497.
11. Pal DC, Jain SK. Tribal Medicine. Calcutta: Naya Prakash; 2000. P. 65-66.
12. Muthukumarasamy S, Mohan VR, Kumaresan S and Chelladurai V, Herbal medicinal plants used by Palliyars to obtain relief from gastro-intestinal complaints, Journal of economic and taxonomic botany, 2003; 27:711-714.
13. Marjana, Mini PP, Remyakrishnan CR, Baiju EC, Ethnomedicinal flowering plants used by Kurumas, Kurichiyas and Paniyas tribes of Wayanad district of Kerala, India, International Journal of Biology Research, 2018; 03:01-08.
14. Minz SS, Kandir K, Folk herbal medicine used for male sterility in Ranchi district of Jharkhand, Journal of Pharmacy and Pharmacology, 2010; 1:56-58.
15. Yadav KS, Yadav NP, Rawat B, Rai VK, Shanker K, Rao CV, An assessment of wound healing potential of Argyreia speciosa leaves, ‎ The Scientific World Journal, 2014; 5:01-06.
16. Singhal AK, Gupta H, Bhati VS, Wound healing activity of Argyreia nervosa leave extract, International Journal of Applied and Basic Medical Research, 2011; 1(1):36-39.
17. Joshi H, Kaur N, Chauhan J, Evaluation of nootropic effect of Argyreia speciosa in mice, Journal of Health Sciences, 2007; 53:382-388.
18. Vyawahare NS, Bodhankar SL, Anticonvulsant activity of Argyreia speciosa in mice, Indian Journal of Pharmaceutical Sciences, 2009; 71:131-134.
19. Subramoniam A, Madhavachandran V, Ravi K, Anju VS, Aphordisiac property of the elephant creeper Argyreia nervosa, Journal of Endocrinology and Reproduction, 2007; 11:5-19.
20. Jaytilak PG, Sheth AR, Mugatwala PP, Pardanani DS, Effect of an indigenous drug (Speman) on human accessory reproductive function, Indian Journal of Surgery, 1976; 38(1):12-15.
21. Mishra M, Mathur A, Testing efficacy of herbal drug “fortege” in treatment of metal induced infertility in male mice, International Journal of Pharmaceutical Sciences and Research, 2013; 4:1521-1523.
22. Gokhale AB, Damre AS, Saraf MN, Investigations into the immunomodulatory activity of Argyreia speciosa, Journal of Ethnopharmacology, 2003; 84:109-114.
23. Suvarna CM, Rao YN, Rao MP, Beeravali SR, Ravindranaik R, Hepatoprotective and anxiolytic activity of methanolic extract of Argyreia nervosa, International Journal of Universal Pharmacy and Bio Sciences, 2013; 2:56-67.
24. Habbu PV, Mahadevan KM, Kulkarni VH, Marietta P, Pratap V, Thippeswamy BS, Veerapur VP, Antidiabetic activity of Argyreia speciosa (sweet) (Burm.f.) Boj. in normoglycemic and streptozotocin-induced diabetic rats, Oriental Pharmacy and Experimental Pharmacy, 2010; 10(2):90-102.
25. Bachhav RS, Gulecha VS, Upasani CD, Analgesic and inflammatory activity of Argyreia speciosa root, Indian Journal of Pharmacology, 2009; 41:158-161.
26. George M, Joseph L, Gupta H, Priya G, Anti-inflammatory and analgesic activity of Argyreia nervosa leaves extract, World Journal of Pharmaceutical Research, 2016; 5:2119-2127.
27. Lalan BK, Hiray RS, Ghongane BB, Evaluation of analgesic and anti-Inflammatory activity of extract of holoptelea integrifolia and Argyreia speciosa in animal models, Journal of Clinical and Diagnostic Research, 2015; 9:01-04.
28. Jeet K, Thakur R, Evaluation of anti-inflammatory activity of whole aerial part-Argyreia nervosa, International Journal of Pharma and Bio Sciences, 2012; 3:150-154.
29. Jeet K, Thakur S, Tomar N, Antipyretic activity of whole aerial part from Argyreia nervosa, International Journal of Pharmacy and Pharmaceutical Sciences, 2012; 4(4):76-77.
30. Ahalawat S, Mishra PK, Dalal K, Patra A, Antipyretic activity of roots of Argyreia speciosa (burm. f.) Bojer, International Journal of PharmTech Research, 2010; 2:2165-2167.
31. Ali SA, Hamed MA, Rigal NS, Shabana MH, Kassem MES. Chemical constituents of Argyreia speciosa Fam. convolvulaceae and its role against hyperglycemia, Journal of Applied Pharmaceutical Science, 2011; 01:76-84.
32. Habbu PV, Mahadevan KM, Kulkarni VH, Marietta P, Pratap V, Thippeswamy BS, Veerapur VP, Antidiabetic activity of Argyreia speciosa (sweet) (Burm.f.) Boj. in normoglycemic and streptozotocin-induced diabetic rats, Oriental Pharmacy and Experimental Pharmacy, 2010; 10(2):90-102.
33. Vivek P, Jayakumari D, Jayasree P, Hypoglycaemic Effect of vriddhadaru [Argyreia nervosa (Burm. f.) Boj.] in alloxan induced diabetic rabbits, International Journal of Advanced Ayurveda, Yoga, Unani, Siddha and Homeopathy, 2016; 5:322-329.
34. Rao V, Ojha SK, Reddy GD, Rawat AKS, Rao GM, Pushpangadan P, Antidiarrhoeal activity of Argyreia speciosa flower: an ethnopharmacological study, Acta Pharmaceutica Sciencia, 2004; 46:149-159.
35. Joshi BB, Chaudhari MG, Kinnari N, Dabhi B, Lal, In-vitro screening of antibacterial and antifungal activity of crude extract of Argyreia nervosa, International Journal of Peptide Research and Therapeutics, 2013; 5:88-96.
36. Mishra SH, Chaturvedi SC, Antibacterial and antifungal activity of the oil and un-saponifiable matter of Argyreia speciosa sweet, Indian Drugs and Pharmaceuticals, 1978; 13:29-31.
37. Shukla YN, Shrivastava A, Kumar S, Kumar S, Phytotoxic and antimicrobial constituents of Argyreia speciosa and Oenothera biennis, Journal of Ethnopharmacology, 1999; 67: 241-245.
38. Babbar OP, Joshi MN, Madan AR, Evaluation of plants for antiviral activity, Indian Journal of Medical Research, 1982; 76:54-65.
39. Sareedenchai V, Wiwat C, Wongsinkongman P, Soonthornchareonnon N, In vitro testing of anti-HIV and antioxidative activities of Argyreia nervosa (Burm.f) Bojor leaves, Pharmaceutical Sciences Asia, 2014; 41:47-53.
40. Parveen N, Khan NU, Singhal KC, Antifilarial activity of Argyreia speciosa against Setaria cervi in vitro, Phototherapy Research, 1990; 4:162-164.
41. Thakur J, Sharma S, Mukhija M, Kalia AN, Flavonoid fraction of Argyreia nervosa leaves with antiulcer potential in different experimental rat models, International Journal of Pharmaceutical Research and Bio-Science, 2013; 2:557-574.
42. Jaiswal SK, Rao CV, Sharma B, Mishra P, Das S, Dubey MK, Gastroprotective effect of standardized leaf extract from Argyreia speciosa on experimental gastric ulcers in rats, Journal of Ethnopharmacology, 2011; 137:341-344.
43. Vyawahare NS, Bodhankar SL, Effect of Argyreia speciosa extract on learning and memory paradigms in mice, Pharmacognosy Magzine, 2009; 4:43-48.
44. Galani VJ, Patel BG, Central nervous system activity of Argyreia speciosa roots in mice, Research Journal of Pharmacy and Technology, 2009; 2:331-334.
45. Vyawahare NS, Pujari R, Kagathara V, Gangurde P, Bodhankar S, Hadambar A, Central nervous system activity of Argyreia speciosa, Journal of Pharmacy Research, 2009; 8:152-158.
46. Mohammed R, Israt JM, Fahmidul H, Ariful HM, Kanta P, Rownak J, Majeedul HC, Taufiq R, An ethnobotanical survey and pharmacological evaluation of medicinal plants used by the garo tribal community living in netrakona district, Bangladesh, International Journal of Natural and Applied Sciences, 2009; 3:402-418.
47. Shiv K, Alagawadi KR, Raghavendra R, Effect of Argyreia speciosa root extract on cafeteria diet induced obesity in rats, Indian Journal of Pharmacology, 2011; 43:163-167.
48. Patil SH, Rajbhoj S, Bhalerao SV, Jha P, Limaye MV, Vaidya MU, A comparative study of efficacy of Argyreia speciosa and orlistat for their anti-obesity action in high fat diet induced obese rats, International Journal of Basic & Clinical Pharmacology, 2017; 6:613-617.
49. Patel NB, Galani VJ, Patel BG, Antistress activity of Argyreia speciosa roots in experimental animals, Journal of Ayurveda and Integrative Medicine, 2011; 2:129-136.
50. Azmi L, Shukla I, Gupta SS, Chaudhary A, Kant P, Yadav NP, Rao CV, Evaluation of chemoprotective effect of quercetin from Argyreia speciosa against N-methyl-N-Nitro-N-nitrosoguanidine and NaCl-induced gastric carcinomas in Wistar Rats, Journal of ‎Pharmacognosy, 2018; 10:215-220.
51. Kaur G, Jaswal P, Banga R, Dharwal V, Kumar A, Naura AS, Hydroalcoholic extract of Argyreia speciosa roots ameliorates HCl-mediated acute lung injury in mice, Pharmacognosy Magzine, 2018; 14:08-13.
47 Views | 77 Downloads
How to Cite
Jaiswal, B. S., & Tailang, M. (2018). PHYTOCHEMISTRY AND PHARMACOLOGICAL PROFILE OF TRADITIONALLY USED MEDICINAL PLANT ARGYREIA SPECIOSA (LINN. F.). Journal of Drug Delivery and Therapeutics, 8(5-s), 41-46.