TOPICAL DELIVERY OF NANOEMULSION FOR ANTIPSORIATIC DRUGS

  • Bharat Khurana 1Nanomedicine Research Centre, Department of Pharmaceutics, I.S.F. College of Pharmacy, Moga (Punjab) India 2Department of Pharmacy, Maharaja Ranjit Singh Punjab Technical University, Bathinda, (Punjab) India
  • Daisy Arora 1Nanomedicine Research Centre, Department of Pharmaceutics, I.S.F. College of Pharmacy, Moga (Punjab) India
  • RK Narang Nanomedicine Research Centre, Department of Pharmaceutics, I.S.F. College of Pharmacy, Moga (Punjab) India

Abstract

Psoriasis is an autoimmune disorder of the skin characterized by relapsing episodes of inflammatory lesions and hyperkeratotic plaques with worldwide occurrence of around 2–5%. Psoriasis is a disease known to be caused by multitude of both genetic and environmental factors such as trauma, drugs, infection, alcohol, smoking and stress but its accurate origin is still not known. Further, available treatment options are associated with both inappropriate cosmetic appearance and related toxicities leading to poor patient compliance in long term use. Nanotechnology based drug delivery system has immense potential to enhance the bioavailability and effectiveness of drugs in their dosage forms, especially lipophilic drugs. Lipid based carrier system can overcome the lipid imbalance and normal moisturizing factors. Nanoemulsions, as one of a new carrier apparently have the prospective to conquer numerous problems related with topical antipsoriatic therapy. This delivery system could perhaps offer a good alternative in topical psoriasis treatment. Not only on how nanoemulsions prepared, but it depends on the active ingredients used and the selection of oil could as well enhance the efficiency of topical treatment towards psoriasis. A good combination of both active and suitable oils would result a better treatment and better effect.


Keywords: Topical nanoemulsion, Antipsoriatic therapy, Critical quality attributes.

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Author Biographies

Bharat Khurana, 1Nanomedicine Research Centre, Department of Pharmaceutics, I.S.F. College of Pharmacy, Moga (Punjab) India 2Department of Pharmacy, Maharaja Ranjit Singh Punjab Technical University, Bathinda, (Punjab) India

1Nanomedicine Research Centre, Department of Pharmaceutics, I.S.F. College of Pharmacy, Moga (Punjab) India

2Department of Pharmacy, Maharaja Ranjit Singh Punjab Technical University, Bathinda, (Punjab) India

Daisy Arora, 1Nanomedicine Research Centre, Department of Pharmaceutics, I.S.F. College of Pharmacy, Moga (Punjab) India

Nanomedicine Research Centre, Department of Pharmaceutics, I.S.F. College of Pharmacy, Moga (Punjab) India

RK Narang, Nanomedicine Research Centre, Department of Pharmaceutics, I.S.F. College of Pharmacy, Moga (Punjab) India

Nanomedicine Research Centre, Department of Pharmaceutics, I.S.F. College of Pharmacy, Moga (Punjab) India

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How to Cite
Khurana, B., Arora, D., & Narang, R. (2018). TOPICAL DELIVERY OF NANOEMULSION FOR ANTIPSORIATIC DRUGS. Journal of Drug Delivery and Therapeutics, 8(5-s), 1-11. https://doi.org/10.22270/jddt.v8i5-s.1914
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Review