REVIEW ON POTENT ANTI-DIABETIC PLANTS OR HERBS FROM TRADITIONAL MEDICINE

  • Shilpa S. Kolhe Bhagwant University, Ajmer Rajastan India
  • Punit R. Rachh Bhagwant University, Ajmer Rajastan India

Abstract

This review focuses on Indian Herbal drugs and plants used in the treatment of diabetes, especially in India. Diabetes is an important human ailment afflicting many from various walks of life in different countries. diabetes is one of the major causes of death and disability in the world. Natural products from medicinal plants, either as pure compounds or as standardized extracts, provide unlimited opportunities for new drug leads because of the unmatched availability of chemical diversity. Due to an increasing demand for chemical diversity in screening programs, seeking therapeutic drugs from natural products, interest particularly in edible plants has grown throughout the world. Botanicals and herbal preparations for medicinal usage contain various types of bioactive compounds. Phytochemicals identified from medicinal plants present an exciting opportunity for the development of new types of therapeutics for diabetes mellitus. Most prevalent among phytochemical groups are the alkaloids, glycosides, polysaccharides, and phenolics such as flavonoids, terpenoids and steroids. These include, Allium sativum, Eugenia jambolana, Momordica charantia Ocimum sanctum, Phyllanthus amarus, Pterocarpus marsupium, Tinospora cordifolia, Trigonella foenum graecum and Withania somnifera.


Keywords: Phytochemicals, diabetes, standardized extracts, bioactive compounds.

Keywords: Phytochemicals, diabetes, bioactive compounds

Downloads

Download data is not yet available.

Author Biographies

Shilpa S. Kolhe, Bhagwant University, Ajmer Rajastan India

Bhagwant University, Ajmer Rajastan India

Punit R. Rachh, Bhagwant University, Ajmer Rajastan India

Bhagwant University, Ajmer Rajastan India

References

1. Saikat Chakraborty R, Biplab D. Challenges and Opportunities in the Advancement of Herbal Medicine: India’s Position and Role in a Global Context. Journal of Herbal Medicine. 2011; 1:76-75
2. Http://Www.Indianmirror.Com/Ayurveda/Pleurisy.Html
3. Grover J.K., Yadav S., Vats V. Medicinal Plants Of India With Antidiabetic Potential. J. Ethnopharmacol. 2002; 81:81–100.
4. Ribeiro C, de Alencar Mota CS, Voltarelli FA, de Araújo MB, Botezelli JD, et al. Effects of Moderate Intensity Physical Training in Neonatal Alloxan- Administered Rats. J Diabetes Metab. 2010; 1:107.
5. da Silva SB, Costa JP, Pintado ME, Ferreira DC, Sarmento B. Antioxidants in the Prevention and Treatment of Diabetic Retinopathy – A Review. J Diabetes Metab. 2010; 1:111.
6. http://www.ncbi.nlm.nih.gov/pubmedhealth/PMH0002194/
7. Ragheb R, Medhat AM. Mechanisms of Fatty Acid-Induced Insulin Resistance in Muscle and Liver. J Diabetes Metab. 2011; 2:127.
8. Mungrue K, Roper LA, Chung T. Assessment of Weight Loss in the Management of Patients with Type 2 Diabetes Mellitus in Primary Care in Trinidad. J Diabetes Metab. 2011; 2:120.
9. Alina S, Barbara R, Krzysztof G, Barbara G, Mare k G, et al. Elevation of sE-Selectin Levels from 2-24 Months Following Gestational Diabetesis Associated with Early Cardiometabolic Risk in Non-Diabetic Women. J Diabetes Metab. 2011; 2:138.
10. Kablan A, Saunders RA, Szkudlarek-Mikho M, Chin JB, Bosio RM, et al. Prieurianin Causes Weight Loss in Diet-Induced Obese Mice and Inhibits Adipogenesis in Cultured Preadipocytes. J Diabetes Metab. 2010; 1:101.
11. Taloyan M, Saleh-Stattin N, Johansson SE, Agréus L, Wändell P. Differences in Cardiovascular Risk Factors in Swedes and Assyrians/Syrians with Type 2 Diabetes: Association with Lifestyle-Related Factors. J Diabetes Metab. 2010; 1:110.
12. Sheela CG, Kumud K, Augusti KT, Anti-diabetic effects of onion and garlic sulfoxide amino acids in rats. Planta Med 1995; 61:356-357.
13. Rajasekaran S, Sivagnanam K, Ravi K, Subramanian S, Hypoglycemic effect of Aloe vera gel on streptozotocin-induced diabetes in experimental rats. J Med Food 2004; 7:61-66.
14. Singh SN, Vats P, Suri S, Shyam R, Kumria MM, et al., Effect of an antidiabetic extract of Catharanthus roseus on enzymic activities in streptozotocin induced diabetic rats. J Ethnopharmacol 2001; 76:269-277
15. Jarvill-Taylor KJ, Anderson RA, Graves DJ, A hydroxychalcone derived from cinnamon functions as a mimetic for insulin in 3T3-L1 adipocytes. J Am Coll Nutr 2001; 20:327-336.
16. Hossain MZ, Shibib BA, Rahman R, Hypoglycemic effects of Coccinia indica: inhibition of key gluconeogenic enzyme, glucose-6-phosphatase. Indian J Exp Biol 1992; 30:418-420.
17. Kumar GP, Sudheesh S, Vijayalakshmi NR, Hypoglycaemic effect of Coccinia indica: mechanism of action. Planta Med 1993; 59:330-332.
18. Augusti KT, Daniel RS, Cherian S, Sheela CG, Nair CR, Effect of leucopelargonin derivative from Ficus bengalensis Linn. on diabetic dogs. Indian J Med Res. 1994; 99:82-86.
19. Yang M, Wang BX, Jin YL, Wang Y, Cui ZY, [Effects of ginseng polysaccharides on reducing blood glucose and liver glycogen]. Zhongguo Yao Li Xue Bao 1990; 11:520-524.
20. Rao BK, Kesavulu MM, Giri R, Appa Rao C, Antidiabetic and hypolipidemic effects of Momordica cymbalaria Hook. fruit powder in alloxan-diabetic rats. J Ethnopharmacol 1999; 67:103-109.
21. Chattopadhyay RR, Hypoglycemic effect of Ocimum sanctum leaf extract in normal and streptozotocin diabetic rats. Indian J Exp Biol 1993; 31:891-893.
22. Kumar A, Iiavarasan R, Jayachadran T, Deecaraman M, Kumar RM, et al., Anti-inflammatory activity of Syzygiumcumini seed. Afr J Biotechnol 2008; 7:941-943.
23. Hannan JMA, Ali L, Rokeya B, Khaleque J, Akhter M, et al. Soluble dietary fibre fraction of Trigonellafoemum-gracecum (fenugreek) seed improves glucose homeostasis in animal models of Type 1 and Type 2 diabetes by delaying carbohydrate digestion and absorption and enhancing insulin action. Br J Nutr 2007; 97:514-521.
24. Padmanabha Rao A, Jamil K, Preclinical Evaluation Of Polyherbal Formulations: Hypoglycemic Activity In Rats International Journal of Ayurvedic And Herbal Medicine 2012; 2(2):218:228.
Statistics
29 Views | 87 Downloads
How to Cite
Kolhe, S. S., & Rachh, P. R. (2018). REVIEW ON POTENT ANTI-DIABETIC PLANTS OR HERBS FROM TRADITIONAL MEDICINE. Journal of Drug Delivery and Therapeutics, 8(5), 92-98. https://doi.org/10.22270/jddt.v8i5.1856