SOFT CHEWABLE DRUG DELIVERY SYSTEM: ORAL MEDICATED JELLY AND SOFT CHEW

  • Ruheena Taranum Student, Department of Pharmaceutics, Deccan School of Pharmacy, Darussalam, Aghapura Hyderabad-01, Telangana, India.
  • Sirisha Mittapally Associate Professor, Department of Pharmaceutics, Deccan School of Pharmacy, Darussalam, Aghapura Hyderabad-01, Telangana, India.

Abstract

Oral route is most commonly used for administration of medicament since they are economical, easy to administer, & high patient acceptance. Due to difficulty in administration of therapeutic agents to dysphagia patients it becomes necessary to develop a formulation in order to overcome such inconvenience. Jellies are semisolid dosage form they are transparent, non greasy, & can be used internally as well as externally. Its matrix include large amount of water & they resemble to mucilage but possess jelly like consistency. Advantages of chewable formulation are that it does not require water for ingestion, aesthetic appearance, and good texture. Soft chew is solid, single dose formulation. It is used as acute medication since it is mobile drug delivery systems. They are formulated using heating & congealing technique. It serves as novel dosage form with wide applications in pharmaceuticals, nutraceuticals and over the counter medicines

Keywords: Jellies, Soft chew, Nutraceuticals

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Author Biographies

Ruheena Taranum, Student, Department of Pharmaceutics, Deccan School of Pharmacy, Darussalam, Aghapura Hyderabad-01, Telangana, India.

Student, Department of Pharmaceutics, Deccan School of Pharmacy, Darussalam, Aghapura Hyderabad-01, Telangana, India.

Sirisha Mittapally, Associate Professor, Department of Pharmaceutics, Deccan School of Pharmacy, Darussalam, Aghapura Hyderabad-01, Telangana, India.
Associate Professor, Department of Pharmaceutics, Deccan School of Pharmacy,  Darussalam, Aghapura Hyderabad-01, Telangana, India.

References

1. Mishra B, Sharma G, Investigation of organoleptic characteristics in the development of soft chews of calcium carbonate as mineral supplement,Yakugaku Zasshi, 2009; 129(12):1537-1544.
2. Raja Manali M, Dhiren P, Oral medicated jelly: a recent advancement in formulation, An international journal of pharmaceutical sciences, 2016; 7(2):13-20.
3. Wikipedia contributors. Alginic acid. Wikipedia, The Free Encyclopedia. May 21, 2018, 02:49 UTC. Available at: https://en.wikipedia.org/w/index.php?title=Alginic_acid&oldid=842229245.
4. Wikipedia contributors. Pectin. Wikipedia, The Free Encyclopedia. June 15, 2018, 14:21 UTC. Available at: https://en.wikipedia.org/w/index.php?title=Pectin&oldid=845988473.
5. Wikipedia contributors. Tragacanth. Wikipedia, The Free Encyclopedia. June 6, 2018, 21:26 UTC. Available at: https://en.wikipedia.org/w/index.php?title=Tragacanth&oldid=844744223.
6. Wikipedia contributors. Gelatin. Wikipedia, The Free Encyclopedia. June 6, 2018, 10:16 UTC. Available at: https://en.wikipedia.org/w/index.php?title=Gelatin&oldid=844670188.
7. Wikipedia contributors. Xanthan gum. Wikipedia, The Free Encyclopedia. June 14, 2018, 15:11 UTC. Available at: https://en.wikipedia.org/w/index.php?title=Xanthan_gum&oldid=845848216.
8. Wikipedia contributors. Carboxymethyl cellulose. Wikipedia, The Free Encyclopedia. June 13, 2018,0:42UTC.Availableat: https://en.wikipedia.org/w/index.php?title=Carboxymethyl_cellulose&oldid=845671169
9. Wikipedia contributors. Agar. Wikipedia, The Free Encyclopedia. June 20, 2018, 17:55 UTC. Available at: https://en.wikipedia.org/w/index.php?title=Agar&oldid=846753815.
10. Wikipedia contributors. Carrageenan. Wikipedia, The Free Encyclopedia. June 25, 2018, 20:24 UTC. Available at: https://en.wikipedia.org/w/index.php?title=Carrageenan&oldid=847502464.
11. Debojyoti B, organoleptic agents: adaptability, acceptability and palatability in formulations to make it lucrative. World Journal of Pharmaceutical Research .2015; (4):1573-1586.
12. Renu, Jyoti D, Chewable Tablets: A Comprehensive Review, The Pharma Innovation Journal, 2015; 4(5):100-105.
13. Eric D, Frank T, Grant E, Sweeteners: discovery, molecular design, and chemoreception, Food/Nahrung, 1991; 35(10):1046
14. Wikipedia contributors. Preservative. Wikipedia, The Free Encyclopedia. June 12, 2018, 05:30 UTC. Available at: https://en.wikipedia.org/w/index.php?title=Preservative&oldid=845498444.
15. Javed H,Shah S,Formulation and Evaluation of Taste Masked Doxycycline HCl Medicated Jelly, Der Pharmacia Sinica, 2017; 8(2):33-39
16. Pundir S, Verma AM, Oral disintegrating preparation - medicated chewing gum, Pharma Utility, 2014, Volume 8.
17. Wikipedia contributors. Candy making. Wikipedia, The Free Encyclopedia. April 30, 2018, 14:15 UTC. Available at: https://en.wikipedia.org/w/index.php?title=Candy_making&oldid=838979532.
18. Available at: http://www.chemistryindustry.biz/emulsifiers.html
19. Wikipedia contributors. Polysorbate 80. Wikipedia, The Free Encyclopedia. May 16, 2018, 08:37 UTC. Available at: https://en.wikipedia.org/w/index.php?title=Polysorbate_80&oldid=841509853.
20. Wikipedia contributors. Sorbitan monostearate. Wikipedia, The Free Encyclopedia. May 24, 2018, Available at: https://en.wikipedia.org/w/index.php?title=Sorbitan_monostearate&oldid=842777923.
21. Rohm H, Schaper C, Zahn S, Interesterified fats in chocolate and bakery products: A concise review,LWT - Food Science and Technology, 2018; 87:379-384.
22. Wikipedia contributors. Condensed milk. Wikipedia, The Free Encyclopedia. June 21, 2018, 17:14UTC.Availablehttps://en.wikipedia.org/w/index.php?title=Condensed_milk&oldid=846914233.
23. Wikipedia contributors. Cream. Wikipedia, The Free Encyclopedia. June 8, 2018, 03:43 UTC. Available at: https://en.wikipedia.org/w/index.php?title=Cream&oldid=844924476.
24. Nanda AR, Garg KS, An update on taste masking technologies for Oral pharmaceuticals, Indian Journal Pharma. sci. 2002; 64(1).
25. Available at http://www.foodadditivesworld.com/
26. Wikipedia contributors. Sodium benzoate. Wikipedia, The Free Encyclopedia. June 13, 2018, 05:05UTC.Availableathttps://en.wikipedia.org/w/index.php?title=Sodium_benzoate&oldid=845642500.
27. Wikipedia contributors. Methylparaben. Wikipedia, The Free Encyclopedia. June 16, 2018, 16:01 UTC. Available at: https://en.wikipedia.org/w/index.php?title=Methylparaben&oldid=846138187
28. Wikipedia contributors. Propylparaben. Wikipedia, The Free Encyclopedia. March 29, 2018, 06:40UTC.Availableat: https://en.wikipedia.org/w/index.php?title=Propylparaben&oldid=833017551.
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How to Cite
Taranum, R., & Mittapally, S. (2018). SOFT CHEWABLE DRUG DELIVERY SYSTEM: ORAL MEDICATED JELLY AND SOFT CHEW. Journal of Drug Delivery and Therapeutics, 8(4), 65-72. https://doi.org/10.22270/jddt.v8i4.1784