IN-VITRO STUDY ON THE HEMOLYTIC ACTIVITY OF DIFFERENT EXTRACTS OF INDIAN MEDICINAL PLANT CROTON BONPLANDIANUM WITH PHYTOCHEMICAL ESTIMATION: A NEW ERA IN DRUG DEVELOPMENT

  • Tanmay Ghosh Department of Microbiology, Rabindra Mahavidyalaya, Champadanga, Hooghly, W.B., India.
  • M K Biswas Department of Plant Protection, Palli Siksha Bhavana, Visva-Bharati, Sriniketan, Birbhum, W.B., India.
  • Sandipan Chatterjee Department of Botany, Suri Vidyasagar College, Suri, Birbhum-731101, West Bengal, India
  • Pradipta Roy Department of Microbiology, Rabindra Mahavidyalaya, Champadanga, Hooghly, W.B., India.

Abstract

In this study different extracts of the leaves of Croton bonplandianum were screened for the haemolytic activity towards human erythrocytes. The haemolytic activity was performed by modified spectroscopic method at four different concentrations (300, 150, 75, 25 μg/ml). The haemolytic activity of the different extracts of Croton bonplandianum was found in the following order Ethyl acetate extract > Chloroform extract > Benzene extract. However, all the extracts alone and in combination with each other exhibited very low haemolytic activity. E. ganitrus did not exhibit any haemolytic activity at any dilution. Hence, they can be considered as safe to human erythrocytes.

Keywords: Hemolytic activity, Croton bonplandianum, Erythrocytes

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Author Biographies

Tanmay Ghosh, Department of Microbiology, Rabindra Mahavidyalaya, Champadanga, Hooghly, W.B., India.
Department of Microbiology, Rabindra Mahavidyalaya, Champadanga, Hooghly, W.B., India.
M K Biswas, Department of Plant Protection, Palli Siksha Bhavana, Visva-Bharati, Sriniketan, Birbhum, W.B., India.
Department of Plant Protection, Palli Siksha Bhavana, Visva-Bharati, Sriniketan, Birbhum, W.B., India.

1. Department of Plant Protection, Palli Siksha Bhavana, Visva-Bharati, Sriniketan, Birbhum, W.B., India.

Sandipan Chatterjee, Department of Botany, Suri Vidyasagar College, Suri, Birbhum-731101, West Bengal, India
Department of Botany, Suri Vidyasagar College, Suri, Birbhum-731101, West Bengal, India
Pradipta Roy, Department of Microbiology, Rabindra Mahavidyalaya, Champadanga, Hooghly, W.B., India.
Department of Microbiology, Rabindra Mahavidyalaya, Champadanga, Hooghly, W.B., India.

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How to Cite
Ghosh, T., Biswas, M., Chatterjee, S., & Roy, P. (2018). IN-VITRO STUDY ON THE HEMOLYTIC ACTIVITY OF DIFFERENT EXTRACTS OF INDIAN MEDICINAL PLANT CROTON BONPLANDIANUM WITH PHYTOCHEMICAL ESTIMATION: A NEW ERA IN DRUG DEVELOPMENT. Journal of Drug Delivery and Therapeutics, 8(4), 155-160. https://doi.org/10.22270/jddt.v8i4.1747