THE EFFECT OF OMEGA® ROOTS + GINSENG ALOE VERA, A NIGERIAN HERBAL MIXTURE, ON HAEMATOLOGICAL PARAMETERS OF NORMAL EXPERIMENTAL RATS

  • Emuesiri Goodies Moke Delta State University, Abraka, Delta State, Nigeria
  • Ighohwo Oghoghovwe Department of Radiography, University of Calabar, Calabar, Cross River State, Nigeria
  • Ejiroghene Ahante Department of Pharmacology and Toxicology, University of Benin, Benin City, Edo State, Nigeria
DOI https://doi.org/10.22270/jddt.v8i3.1742

Abstract

Omega® Roots + Ginseng Aloe Vera herbal mixture is a commonly sold herbal formulation used for treatment of ailments. The aim of this study is to evaluate the toxic effect of Omega® Roots herbal mixture on the haematological parameters of Wistar rats. Twenty rats were used for this study and were divided into four groups of 5 animals each; the control group was administered normal saline 10 ml/kg, and the treated groups received 250 mg/kg, 500 mg/kg, and 1000 mg/kg of the herbal mixture (Omega® Roots) a period of fourteen days after which blood samples were collected for haematological analysis. The results of this study showed that oral administration of the Omega® Roots extract had a non-significantly (P˃0.05) change in the red blood cell count, white blood cell count, packed cell volume, and hemoglobin concentration of the Wistar rats. The findings suggest that Omega® Roots + Ginseng Aloe Vera herbal mixture is non-haematotoxic following acute administration.

Keywords: Omega® Roots, herbal mixture, non-haematotoxic, phytomedicine

Downloads

Download data is not yet available.

Author Biographies

Emuesiri Goodies Moke, Delta State University, Abraka, Delta State, Nigeria

Department of Pharmacology and Therapeutics, Delta State University, Abraka, Delta State, Nigeria

 

Ighohwo Oghoghovwe, Department of Radiography, University of Calabar, Calabar, Cross River State, Nigeria

Department of Radiography, University of Calabar, Calabar, Cross River State, Nigeria

Ejiroghene Ahante, Department of Pharmacology and Toxicology, University of Benin, Benin City, Edo State, Nigeria

Department of Pharmacology and Toxicology, University of Benin, Benin City, Edo State, Nigeria

References

1. Aliyu R, Adebayo AH, Gatsing D, Garba IH. The Effect of Ethanolic Leaf Extract of Commiphora Africana (Burseraceae) on Rat Liver Functions. Journal of Pharmacology and Toxicology. 2007; 2:373-379.
2. Nostro A, Germano MP, D’Angelo A, Marino A, Cannatelli MA. Extraction methods and bioautography for evaluation of medicinal plant antimicrobial activity. Letters of Applied Microbiology. 2000; 30(5):379–385.
3. Idu M, Omogbai EKI, Amaechina FC, Ataman JE. Some cardiovascular effects of aqueous extract of the leaves of Stachytapheta jamaiciens (L) Vahl. International Journal of Pharmacology. 2006; 2:163-165.
4. Okigbo RN, Mmeka EC. An Appraisal of Phytomedicine in Africa. KMITL Science and Technology Journal. 2006; 6:83-94.
5. Phua DH, Zosel A, Heard K. Dietary supplements and herbal medicines toxicities – when to anticipate them amd how to manage them. Int J Emerg Med. 2009; 2(2): 69-76
6. Efferth T, Kaina B. Toxicities by herbal medicines with emphasis to traditional Chinese medicine. Curr. Drug Metab. 2011; 12(10):989-996
7. Timbrell J. Principles of Biochemical Toxicology. 3rd ed. USA: Taylor and Francis Ltd; 2000.
8. Baker FI, Silverton RE, Pallister CJ. Baker and Silvertons Introduction to Medical Laboratory Technology. 7th ed. Nigeria: Bounty Press Ltd; 1998. P. 339-373.
9. Ochei J, Kolhatkar A. Complete blood count. Medical Laboratory Sciences. 6th ed. M. Graw Hill publishing company Limited; 2007. P. 273-283.
Statistics
1779 Views | 713 Downloads
How to Cite
1.
Moke E, Oghoghovwe I, Ahante E. THE EFFECT OF OMEGA® ROOTS + GINSENG ALOE VERA, A NIGERIAN HERBAL MIXTURE, ON HAEMATOLOGICAL PARAMETERS OF NORMAL EXPERIMENTAL RATS. JDDT [Internet]. 14May2018 [cited 10Aug.2022];8(3):29-1. Available from: http://jddtonline.info/index.php/jddt/article/view/1742
Issue
Vol 8 No 3 (2018): VOLUME 8, ISSUE 3, MAY-JUNE 2018
Section
Research

Authors who publish with this journal agree to the following terms:

  1. Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0). that allows others to share the work with an acknowledgment of the work's authorship and initial publication in this journal.
  2. Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgment of its initial publication in this journal.
  3. Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).