ADVERSE DRUG REACTIONS: A COMPREHENSIVE REVIEW

  • Rajeev Kumar IIMT College of Pharmacy Greater Noida
  • Shivani Singh LIMT Department of Pharmacy, Greater Noida
  • Sudhir Arora IIMT College of Pharmacy Greater Noida
  • Savita Bhati LIMT Department of Pharmacy, Greater Noida

Abstract

Adverse drug reactions are the undesirable unintended response of the drug which occurs at the doses normally used for the diagnosis, prophylaxis and treatment of the patient. ADR is the harmful effect other than desirable or expected which can vary from desirable from mild to severe reaction, even sometimes responsible for causing considerable morbidity and mortality. The reasons include overdose, polypharmacy, diseased condition etc. to name few among them. The increased ADR rate is highly alarming and thus requires proper monitoring and reporting of ADR to the concerned regulatory authorities. In this review we try to cover different aspects of adverse drug reactions like its types, factors affecting ADR, reasons for increasing rate of ADR, preventive measures and also the monitoring and reporting of ADR.

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Author Biographies

Rajeev Kumar, IIMT College of Pharmacy Greater Noida
Assistant Professor Department of Pharmacy, IIMT College of Pharmacy, A-20 Knowledge Park 3, Greater Noida, U.P., India-201308
Shivani Singh, LIMT Department of Pharmacy, Greater Noida
Assistant Professor Department of Pharmacy, LIMT Department of Pharmacy, Greater Noida, U.P., India-201308
Sudhir Arora, IIMT College of Pharmacy Greater Noida
Assistant Professor Department of Pharmacy, IIMT College of Pharmacy, A-20 Knowledge Park 3, Greater Noida, U.P., India-201308
Savita Bhati, LIMT Department of Pharmacy, Greater Noida
Assistant Professor Department of Pharmacy, LIMT Department of Pharmacy, Greater Noida, U.P., India-201308

LIMT Department of Pharmacy, Greater Noida, U.P., India-201308

References

1. Jeffrey KA, Robin EF. Clarification of terminology in drug safety. Drug Saf. 2005; 28:851-70.
2. Abubakar AR, Simbak NB, Haque M. Adverse Drug Reactions: predisposing factors, modern classifications and causality assessment. Research J. Pharm. 2014; 7(9):1091-1098.
3. Edwards IR, Jeffrey KA. Adverse drug reactions: definitions, diagnosis, and management. The Lancet. 2000; 255-59.
4. Dhikav V, Singh S, Anand KS. Adverse Drug Reaction Monitoring In India. JIACM 2004; 5(1): 27-33.
5. Pallasch TJ. Principles of Pharmacotherapy V. Toxicology and Adverse Drug Reactions. Anesth Prog. 1989; 36:41-45.
6. Lavan AH, Gallagher P. Predicting risk of adverse drug reactions in older adults. Ther Adv Drug Saf. 2016; 7(1):11–22.
7. Schatz SN, Weber RJ. Adverse Drug Reaction. CNS/Pharmacy Practice. 2015; 5-22.
8. Coleman JJ, Pontefrac SK. Adverse drug reactions. Clinical Medicine. 2016; 481-5.
9. Jordan S, Vaismoradi M, Griffiths P. Adverse Drug Reactions, Nursing and Policy: A Narrative Review. Ann Nurs Pract. 2016; 3(3): 1050.
10. Bfrahma DK, Wahlang JB, Marak MD, Snagma MC. Adverse drug reactions in the elderly. J Pharmacol Pharmacother. 2013; 4(2): 91-94.
11. Alomar MJ. Factors affecting the development of adverse drug reactions. Saudi Pharmaceutical Journal. 2014; 22, 83-94.
12. Bhosale VV, Gaur SPS. Adverse drug reaction monitoring. Current SC 1024 Ience, 2011; 1024-1027.
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How to Cite
1.
Kumar R, Singh S, Arora S, Bhati S. ADVERSE DRUG REACTIONS: A COMPREHENSIVE REVIEW. JDDT [Internet]. 15Jan.2018 [cited 27Nov.2021];8(1):103-7. Available from: http://jddtonline.info/index.php/jddt/article/view/1658