WOUND HEALING ACTIVITY OF THE HYDRO-ALCOHOLIC EXTRACT OF DATURA STRAMONIUM LEAVES IN WISTAR ALBINO RATS

  • Priyanshu Shekhar Modern Institute of Pharmaceutical Sciences, Indore (M.P.), India, 453111
  • Ankur Joshi Modern Institute of Pharmaceutical Sciences, Indore (M.P.), India, 453111
  • Sapna Malviya Modern Institute of Pharmaceutical Sciences, Indore (M.P.), India, 453111
  • Anil Kharia Modern Institute of Pharmaceutical Sciences, Indore (M.P.), India, 453111

Abstract

Datura Stramonium has been known for many potential uses. Leaves of datura are used in herbal medicine especially in case of Ayurveda for asthma and bonesetting. Roasted leaves is applied over the area of relieve pain. Leaves and leaves are used in antiasthematic, antispasmodic, hypnotic & narcotic. The hydro-alcoholic extract of Datura Stramonium leaves were investigated for wound healing potential in rats. Datura Stramonium leaves were dried, crushed in coarse powder hydro-alcoholic extract was obtained and turned to 10% ointment form. In the course of this study, 18 male wistar albino rats weighing approximately 150- 180g were used in this research. Group 1 as control group, Group 2 as reference control were treated topically with Povidone-Iodine Ointment USP, Group3 as test control were treated with 10% Datura Stramonium ointment. Wound healing was monitored on days 4,8,12,16 and histopathological evaluation was carried out on the samples. Leaf extract of Datura Stramonium promotes wound healing via bactericidal activity.

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Author Biographies

Priyanshu Shekhar, Modern Institute of Pharmaceutical Sciences, Indore (M.P.), India, 453111

Modern Institute of Pharmaceutical Sciences, Indore (M.P.), India, 453111

Ankur Joshi, Modern Institute of Pharmaceutical Sciences, Indore (M.P.), India, 453111

Modern Institute of Pharmaceutical Sciences, Indore (M.P.), India, 453111

Sapna Malviya, Modern Institute of Pharmaceutical Sciences, Indore (M.P.), India, 453111

Modern Institute of Pharmaceutical Sciences, Indore (M.P.), India, 453111

Anil Kharia, Modern Institute of Pharmaceutical Sciences, Indore (M.P.), India, 453111

Modern Institute of Pharmaceutical Sciences, Indore (M.P.), India, 453111

References

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How to Cite
Shekhar, P., Joshi, A., Malviya, S., & Kharia, A. (2017). WOUND HEALING ACTIVITY OF THE HYDRO-ALCOHOLIC EXTRACT OF DATURA STRAMONIUM LEAVES IN WISTAR ALBINO RATS. Journal of Drug Delivery and Therapeutics, 7(7), 214-215. https://doi.org/10.22270/jddt.v7i7.1641