EVALUATION OF ANTI PSORIATIC ACTIVITY OF KARANJIN OIL
Psoriasis is defined as a type of severe inflammatory and autoimmune skin disease, caused due to genetic and natural/surrounding factors and the most successful way to tackle this disease is topical treatment. To examine potency of the herbal drug in the cure of psoriasis like lesions on mice skin is the core objective of this study. Imiquimod model of psoriasis was used in the evaluation of the drug and the qRT-PCR was done to check cytokines concentration in the blood serum of psoriasis induced mice. The drug karanjin oil was proved to have anti-psoriatic activity.Â
2. Gudjonsson JE, Johnston A, Dyson M, Valdimarsson H, Elder JT, Mouse models of psoriasis, J Inv Dermatol, 2007, 127, 1292-1308.
3. Schon MP, Boehncke WH, Psoriasis, NEJM, 2005, 352, 1899-1912.
4. Lowes MA, Bowcock AM, Krueger JG, Pathogenesis and therapy of psoriasis, Nature, 2007, 445, 866-873.
5. Yadav PP, Ahmad GA, Maurya R, Furanoflavonoids from Pongamia pinnata fruits Phytochemistry, 2004, 65, 429- 442.
Authors who publish with this journal agree to the following terms:
- Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License. that allows others to share the work with an acknowledgment of the work's authorship and initial publication in this journal.
- Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgment of its initial publication in this journal.
- Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (SeeÂ The Effect of Open Access).