EVALUATION OF ANTI PSORIATIC ACTIVITY OF KARANJIN OIL

  • Thomson Alex Smriti College of Pharmaceutical Education, Indore (Madhya Pradesh), India
  • Shabnam Mansuri Smriti College of Pharmaceutical Education, Indore (Madhya Pradesh), India
  • Shaily Chaudhary Smriti College of Pharmaceutical Education, Indore (Madhya Pradesh), India
  • Neelesh Malviya Smriti College of Pharmaceutical Education, Indore (Madhya Pradesh), India

Abstract

Psoriasis is defined as a type of severe inflammatory and autoimmune skin disease, caused due to genetic and natural/surrounding factors and the most successful way to tackle this disease is topical treatment. To examine potency of the herbal drug in the cure of psoriasis like lesions on mice skin is the core objective of this study. Imiquimod model of psoriasis was used in the evaluation of the drug and the qRT-PCR was done to check cytokines concentration in the blood serum of psoriasis induced mice. The drug karanjin oil was proved to have anti-psoriatic activity. 

Downloads

Download data is not yet available.

Author Biographies

Thomson Alex, Smriti College of Pharmaceutical Education, Indore (Madhya Pradesh), India

Smriti College of Pharmaceutical Education, Indore (Madhya Pradesh), India

Shabnam Mansuri, Smriti College of Pharmaceutical Education, Indore (Madhya Pradesh), India

Smriti College of Pharmaceutical Education, Indore (Madhya Pradesh), India

Shaily Chaudhary, Smriti College of Pharmaceutical Education, Indore (Madhya Pradesh), India

Smriti College of Pharmaceutical Education, Indore (Madhya Pradesh), India

Neelesh Malviya, Smriti College of Pharmaceutical Education, Indore (Madhya Pradesh), India

Smriti College of Pharmaceutical Education, Indore (Madhya Pradesh), India

References

1. Van der Fits L, Mourits S, Voerman JSA, Kant M, Boon L, Laman JD, Imiquimod-induced psoriasis-like skin inflammation in mice is mediated via IL-23/IL-17 axis, JI, 2009, 182, 54-58.
2. Gudjonsson JE, Johnston A, Dyson M, Valdimarsson H, Elder JT, Mouse models of psoriasis, J Inv Dermatol, 2007, 127, 1292-1308.
3. Schon MP, Boehncke WH, Psoriasis, NEJM, 2005, 352, 1899-1912.
4. Lowes MA, Bowcock AM, Krueger JG, Pathogenesis and therapy of psoriasis, Nature, 2007, 445, 866-873.
5. Yadav PP, Ahmad GA, Maurya R, Furanoflavonoids from Pongamia pinnata fruits Phytochemistry, 2004, 65, 429- 442.
Statistics
94 Views | 108 Downloads
How to Cite
Alex, T., Mansuri, S., Chaudhary, S., & Malviya, N. (2017). EVALUATION OF ANTI PSORIATIC ACTIVITY OF KARANJIN OIL. Journal of Drug Delivery and Therapeutics, 7(7), 206-207. https://doi.org/10.22270/jddt.v7i7.1638