UV SPECTROPHOTOMETRIC DETERMINATION OF PIPERINE IN NAVASAYA CHURNA: A POLYHERBAL FORMULATION

  • Nirmal Dongre Indore Institute of Pharmacy, Indore, M.P., India
  • Pankaj Sharma School of Pharmacy, Jaipur National University, Jaipur, Rajasthan, India
  • Birendra Shrivastava School of Pharmacy, Jaipur National University, Jaipur, Rajasthan, India
  • P K Dubey Swami Vivekananda College of Pharmacy, Indore, M.P., India

Abstract

Navayasa Churna is an important ayurvedic formulation, is mentioned in Bhaishajyaratnavali in Pandu roga chikitsa iscombination of Nine i.e. Amlaki, Bibhitaka, Haritaki, Marica Pippali, Sunth, Chitraka, Musta, Vidanga and Lauha bhasma. The formulation is dispensed for the treatment of Anemia (pandu), Hepatoprotective and Liver disorders. The method for spectrophotometric determination of piperine from the fruits of Piper longum, Piper nigrum and Navasaya Churna has been developed at absorption maxima 342.7nm. The concentration of piperine present in raw material was found to be 2.981 ± 0.38 % (w/w) in marica and 0.981 ± 0.047 % (w/w) in pippali, respectively and in three identical laboratory batch of Navasaya churna name NY-I, NY-II, and NY-III, was 0.223 ± 0.34, 0.219 ± 0.42, 0.215 ± 0.43 % (w/w), respectively with mean value 0.219 ± 0.903 % (w/w). The piperine content of all the three batches is found to be in close proximities with each other.

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Author Biographies

Nirmal Dongre, Indore Institute of Pharmacy, Indore, M.P., India

Indore Institute of Pharmacy, Indore, M.P., India

Pankaj Sharma, School of Pharmacy, Jaipur National University, Jaipur, Rajasthan, India
School of Pharmacy, Jaipur National University, Jaipur, Rajasthan, India
Birendra Shrivastava, School of Pharmacy, Jaipur National University, Jaipur, Rajasthan, India
School of Pharmacy, Jaipur National University, Jaipur, Rajasthan, India
P K Dubey, Swami Vivekananda College of Pharmacy, Indore, M.P., India

Swami Vivekananda College of Pharmacy, Indore, M.P., India

References

1. Bhaisajyaratnavali, Chowkhamba Sanskrit Series Office, Varanasi, 1961, Sloke, edn2 35:19.
2. World Health Organization, Quality Control Methods for Medicinal Plants Materials, Geneva, 1998, 1-15.
3. The Ayurvedic Pharmacopoeia of India, 1999, Part I Vol 2 1133.
4. Jain V, Saraf SS, Spectrophotometric determination of piperine in Trikatu churna: an ayurvedic formulation, AJC, 2007, 19, 5331-5335.
5. Dongre N, Dubey PK, Shrivastava B, Pharmacognostical, Physicochemical and Chromatographic Evaluation of Polyherbal Formulation: Navasaya Churna, IJPLS, 2017, 11(8):44.
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How to Cite
Dongre, N., Sharma, P., Shrivastava, B., & Dubey, P. (2017). UV SPECTROPHOTOMETRIC DETERMINATION OF PIPERINE IN NAVASAYA CHURNA: A POLYHERBAL FORMULATION. Journal of Drug Delivery and Therapeutics, 7(7), 186-188. https://doi.org/10.22270/jddt.v7i7.1630