DOCKING, SYNTHESIS AND EVALUATION OF NOVEL DERIVATIVES OF SUBSTITUTED CHALCONES AS ANTIHYPERGLYCEMIC AGENTS

  • Ankit Jain IPS Academy College of Pharmacy, Indore-452012 (M.P.) India
  • D K Jain IPS Academy College of Pharmacy, Indore-452012 (M.P.) India

Abstract

Various substituted chalcone derivatives (4A-4E) were synthesized. The structures of these compounds were established by spectral (IR, 1H-NMR, Mass) analysis. The synthesized compounds were screened for their antihyperglycemic activity. Compound 4-C (2-(3-(4-methoxyphenyl)-1H-pyrazol-5-yl) phenol) was found to possess potent antihyperglycemic activity.

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Author Biographies

Ankit Jain, IPS Academy College of Pharmacy, Indore-452012 (M.P.) India
IPS Academy College of Pharmacy, Indore-452012 (M.P.) India

D K Jain, IPS Academy College of Pharmacy, Indore-452012 (M.P.) India
IPS Academy College of Pharmacy, Indore-452012 (M.P.) India

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How to Cite
1.
Jain A, Jain D. DOCKING, SYNTHESIS AND EVALUATION OF NOVEL DERIVATIVES OF SUBSTITUTED CHALCONES AS ANTIHYPERGLYCEMIC AGENTS. JDDT [Internet]. 22Dec.2017 [cited 5Jul.2020];7(7):154-7. Available from: http://jddtonline.info/index.php/jddt/article/view/1618