VALIDATED RP HPLC METHOD DEVELOPMENT FOR EXEMESTANE IN TABLET DOSAGE FORM

  • Deepak Kumar Gupta Dr. APJ Abdul Kalam University, Indore (M.P.) India
  • Prakash Panday Dr. APJ Abdul Kalam University, Indore (M.P.) India
  • Revati Gupta Dr. APJ Abdul Kalam University, Indore (M.P.) India

Abstract

The aim of this present work was to develop stability indicating LC method, which is selective, accurate, simple, precise, reliable, cost effective and rapid for the quantification of all possible degradants and determination of exemestane. In addition, to develop and validate Stability Indicating Method for the determination of impurities (degradation products) in exemestane API by RP-HPLC. Finally, validate the developed method as per ICH guidelines.

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Author Biographies

Deepak Kumar Gupta, Dr. APJ Abdul Kalam University, Indore (M.P.) India
Dr. APJ Abdul Kalam University, Indore (M.P.) India
Prakash Panday, Dr. APJ Abdul Kalam University, Indore (M.P.) India

Dr. APJ Abdul Kalam University, Indore (M.P.) India

Revati Gupta, Dr. APJ Abdul Kalam University, Indore (M.P.) India

Dr. APJ Abdul Kalam University, Indore (M.P.) India

References

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2. Conners KA, A Textbook of Pharmaceutical Analysis, A Wiley- Interscience Publication, 1999, 3rd ed., 373-374.
3. Chatwal GR, Anand SK, Instrumental Methods of Chemical Analysis, Himalaya Publishing House, 2004, 2, 110.
4. Sethi PD, In; HPLC ‘High Performance Liquid Chromatography’, Quantitative Analysis of Pharmaceutical Formulations, CBS Publishers and Distributors, New Delhi, 2001, 3rd ed., 72, 116-120.
5. Snyder LR, Kirkland JJ, Glajch LJ, Practical HPLC Method Development, A Wiley-Interscience publication, New York, 1997, 2nd ed., 33:35.
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How to Cite
Gupta, D., Panday, P., & Gupta, R. (2017). VALIDATED RP HPLC METHOD DEVELOPMENT FOR EXEMESTANE IN TABLET DOSAGE FORM. Journal of Drug Delivery and Therapeutics, 7(7), 110-112. https://doi.org/10.22270/jddt.v7i7.1603