FORMULATION AND EVALUATION OF TABLETS CONTAINING ARTEMETHER MICROSPHERES AND LUMEFANTRINE

  • Kuldeep Vinchurkar IPS Academy College of Pharmacy, Indore - 452012 (M.P.), India
  • Sheetal Mane IPS Academy College of Pharmacy, Indore - 452012 (M.P.), India
  • Neelam Balekar IPS Academy College of Pharmacy, Indore - 452012 (M.P.), India
  • D K Jain IPS Academy College of Pharmacy, Indore - 452012 (M.P.), India

Abstract

This study was aimed to fabricate and evaluate a combination of Artemether and Lumefantrine as tablets and to make Artemether in sustained form so as to prolong its elimination time. Artemether was formulated in form of microspheres by solvent evaporation technique and was then formed into the tablet along with the Lumefantrine. Artemether microspheres were prepared and compressed into compressible tablet by direct compression process using the compressible excipients along with Lumefantrine, and was further evaluated for various parameters such as hardness, thickness, weight variation, friability, drug content, in vitro drug release and stability.

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Author Biographies

Kuldeep Vinchurkar, IPS Academy College of Pharmacy, Indore - 452012 (M.P.), India

IPS Academy College of Pharmacy, Indore - 452012 (M.P.), India

Sheetal Mane, IPS Academy College of Pharmacy, Indore - 452012 (M.P.), India

IPS Academy College of Pharmacy, Indore - 452012 (M.P.), India

Neelam Balekar, IPS Academy College of Pharmacy, Indore - 452012 (M.P.), India

IPS Academy College of Pharmacy, Indore - 452012 (M.P.), India

D K Jain, IPS Academy College of Pharmacy, Indore - 452012 (M.P.), India

IPS Academy College of Pharmacy, Indore - 452012 (M.P.), India

References

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How to Cite
Vinchurkar, K., Mane, S., Balekar, N., & Jain, D. (2017). FORMULATION AND EVALUATION OF TABLETS CONTAINING ARTEMETHER MICROSPHERES AND LUMEFANTRINE. Journal of Drug Delivery and Therapeutics, 7(7), 4-7. https://doi.org/10.22270/jddt.v7i7.1569