Pharmacognostical and Phytochemical evaluation of root of Asparagus racemosus Willd.

  • Md. Parwez Ahmad Department of Pharmacology, National Medical College, Birgunj, Nepal
  • Arshad Hussain Faculty of Pharmacy, King Khalid University, KSA
  • Shadma Wahab Faculty of Pharmacy, King Khalid University, KSA
  • Akhtar Alam Ansari Department of Pharmacology, National Medical College, Birgunj, Nepal
  • Smita Singh Department of Pharmacology, National Medical College, Birgunj, Nepal
  • Chandan Mishra Department of Pharmacology, National Medical College, Birgunj, Nepal
  • Shafique Ahmad Department of Pharmacology, Faculty of Pharmacy, Hamdard University, New Delhi, India

Abstract

Aim of this is to examine the Pharmacognastical and Phytochemical properties of Asparagus racemosus. The qualitative microscopy, Phytochemical screening, physicochemical evolution, fluorescence analysis and HPTLC studies were carried out according to the standard procedure recommended in WHO guidelines. The root had compactly arranged, uniseriate, polygonal to radially elongated, thick walled cell represent the outermost piliferous layer. Immediately laying below the epidermis is extensively developed, several layers of thick cortex made up of parenchymatous cells. The cortical cells contain raphide bundles. The innermost one or two layer of cortex immediately outside the endodermis comprises thick-walled cells, with the numerous oval or circular pits on their walls. Endodermis is composed of a single layer of compactly arranged, barrel-shaped parenchymatous cells. Inner to endodermis is a single layer of thin-walled, parenchymatous cells constituting the pericycle in the form of a ring, which surrounds a central stele. Phytochemical investigation of root shows total ash (6.5 %w/w), acid insoluble ash (1.3% w/w), and water-soluble ash (2.2% w/w).  Loss on drying is (5.5% w/w). Cold extractive value in pet, ether (0.5%% w/w) in chloroform (3.4% w/w), methanol (8.0 % w/w) and in water (10.2% w/w). Hot extractive value in pet. ether (0.9% w/w),  in chloroform (4.6 % w/w), methanol (10.40 % w/w) and  in water  (11.2% w/w). In methanolic extract and aqueous extract, tannins and saponins present in a major amount. Other constituents include carbohydrate, glycosides and phenolic compounds were present. Various pharmacognistical parameters evaluated in this study help in identification and standardization of the root of Asparagus racemosus.

Keywords:  Asparagus racemosus Willd, Satavar; Phytochemical investigation, Phytochemistry

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Author Biographies

Md. Parwez Ahmad, Department of Pharmacology, National Medical College, Birgunj, Nepal

Department of Pharmacology, National Medical College, Birgunj, Nepal

Arshad Hussain, Faculty of Pharmacy, King Khalid University, KSA

Faculty of Pharmacy, King Khalid University, KSA

Shadma Wahab, Faculty of Pharmacy, King Khalid University, KSA

Faculty of Pharmacy, King Khalid University, KSA

Akhtar Alam Ansari, Department of Pharmacology, National Medical College, Birgunj, Nepal

Department of Pharmacology, National Medical College, Birgunj, Nepal

Smita Singh, Department of Pharmacology, National Medical College, Birgunj, Nepal

Department of Pharmacology, National Medical College, Birgunj, Nepal

Chandan Mishra, Department of Pharmacology, National Medical College, Birgunj, Nepal

Department of Pharmacology, National Medical College, Birgunj, Nepal

Shafique Ahmad, Department of Pharmacology, Faculty of Pharmacy, Hamdard University, New Delhi, India

Department of Pharmacology, Faculty of Pharmacy, Hamdard University, New Delhi, India

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How to Cite
Ahmad, M., Hussain, A., Wahab, S., Ansari, A., Singh, S., Mishra, C., & Ahmad, S. (2017). Pharmacognostical and Phytochemical evaluation of root of Asparagus racemosus Willd. Journal of Drug Delivery and Therapeutics, 7(6), 76-80. https://doi.org/10.22270/jddt.v7i6.1524