AMELIORATIVE EFFECT OF BAMBUSA ARUNDINACEA AGAINST ADJUVANT ARTHRITIS-WITH SPECIAL REFERENCE TO BONE EROSION AND TROPICAL SPLENOMEGALY

  • Jaimik D Rathod PG & Research Dept. of Pharmacology C.U.Shah College of Pharmacy & Research, Wadhwan, Gujarat, INDIA

Abstract

Complete Freund’s Adjuvant (CFA)-induced arthritis is a commonly used model in the rat. Sub-planter injection of CFA caused a localized inflammatory reaction to develop in 24 hr. In the present study, the effect of Bambusa arundinacea Methanolic extract on the Arthritis was studied by analyzing various markers of Bone erosion like histological, radiological analysis of the joints, Paw volume, ESR and Spleen histopathology in Freund’ complete adjuvant induced- arthritis in rats. The powdered leaves are used for hot extraction by using methanol as solvent. The Anti-arthritic activity of the dry extracts was performed using female rats of about 200 to 250gms. The Methanolic extract of Bambusa arundinacea significantly (dose dependent) decreased the bone erosion, spleen enlargement & rheumatoid factor etc. at a dose (100mg/kg, 200mg/kg, 300mg/kg) compared to the control group

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Author Biography

Jaimik D Rathod, PG & Research Dept. of Pharmacology C.U.Shah College of Pharmacy & Research, Wadhwan, Gujarat, INDIA
PG & Research Dept. of Pharmacology C.U.Shah College of Pharmacy & Research, Wadhwan, Gujarat, INDIA
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1.
Rathod J. AMELIORATIVE EFFECT OF BAMBUSA ARUNDINACEA AGAINST ADJUVANT ARTHRITIS-WITH SPECIAL REFERENCE TO BONE EROSION AND TROPICAL SPLENOMEGALY. JDDT [Internet]. 14May2012 [cited 29Nov.2021];2(3). Available from: http://jddtonline.info/index.php/jddt/article/view/150