PHARMACEUTICAL STANDARDIZATION OF BALADI MANDURAM
Objective: Baladi Manduram (BM) is one of the most impairment and potent herbo-mineral formulation described in Ayurvedic classics viz., Rasa Kamadhenu and Rasayoga sagara specified for the management of the disease Amlapitta. BM contains Mandura Bhasma, Balamula, Satavarimula, Erandamula, Yava, Pippali, Jiraka, Twak, Ela, Patra, Nagakesara and Guda. Till now no research work has been carried out to standardize the preparation of BM. The main objective of the present study is to standardize the method of preparation of BM according to the conventional method mentioned in classical literatures.
Methods: Shodhana, Bhavana, Marana, Churna nirmana and Paka are the main pharmaceutical procedures involved in the preparation of BM. Mandura was subjected to Shodhana by Nirvapa in Gomutra Triphala Kashaya for 7 times. Shodhita Mandura thus obtained was triturated with Kumari Swarasa and subjected to Gaja puta for 7 times. Mandura Bhasma thus otained was added to the guda paka along with the fine powders of herbal ingredients. Then the homogenous mixture of BM was made in the form of capsules of 500mg.
Results: 1380 g of BM was prepared from 1264g of Mandura Bhasma, 100g each of Balamula, Satavarimula, Erandamula and Yava, 50g each of Pippali and Jiraka and 8g each of Twak, Ela, Patra and Nagakesara.
Conclusion: All these procedures can be considered ideal in the standardization of the preparation of Baladi Manduram.Keywords: Baladi Manduram, Shodhana, Bhavana, Marana, Churna nirmana, Paka, Standardization.
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