PRELIMINARY PHARMACOGNOSTICAL AND PHYTOCHEMICAL EVALUATION OF AROGYAVARDHINI COMPOUND- AN EMERGING FORMULATED MEDICINE FOR METABOLIC SYNDROME

  • Bharatkumar Chhaganbhai Padhar Ph.D Scholar Kayahikitsa Department I.P.G.T and R.A Gujarat Ayurved University Jamnagar 361008
  • Alankruta R Dave Associate Prof. & I/C Head of Department of Kayachikitsa, I.P.G.T & R.A, Gujarat Ayurved University Jamnagar, India
  • C R Harisha Head of Pharmacognosy laboratory, I.P.G.T & R.A, Gujarat Ayurved University Jamnagar, India
  • V J Shukla Head of Pharmaceutical laboratory, I.P.G.T & R.A, Gujarat Ayurved University Jamnagar, India

Abstract

Context: Arogyavardhini Compound is an emerging formulated herbo-mineral formulation for treatment of metabolic syndrome. Metabolic syndrome is group of risk factors like, increased waist circumference, insulin resistance, increased triglycerides, decreased high density lipoproteins and hypertension for coronary artery diseases and type 2 diabetes mellitus. Arogyavardhini compound consist equal quantity of Arogyavardhini Rasa and single bulb garlic powder. Arigyavardhini Rasa having proven anti dyslipidemiac and weight reducing effect and Garlic having antidiabetic, antidyslipidemic, antihypertensive effect, the combination called Arogyavardhini Compound has been formulated for management of metabolic syndrome. Aim: Authentication of raw drug of Arogyavardhini Compound and phytochemical evaluation of finished product. Materials and methods: Arogyavardhini Compound was evaluated on the basis of powder microscopy and analytical parameters like pH, Ash value, acid insoluble ash, water soluble extract, methanol extract and high performance thin layer chromatography. Results: Powder microscopy revealed the presence of Annular vessels of Musta, Starch grains of Vacha, Stone cells of Pippali, Stone cells of Chitraka, Oleoresins of Shunthi, etc. Physicochemical parameters such as total Ash value (15.91%), water soluble extract (13.5%), methanol soluble extract (17.2%) were assessed in preliminary physicochemical scanning. HPTLC revealed maximum 09 spots in short wave UV 254 nm. and 07 spots were obtained in long wave UV 366 nm. Conclusion: Pharmacognostical study revealed genuinity of raw drugs. Physico-chemical and HPTLC studies inferred that the formulation meets the minimum quality standards as reported in the API at a preliminary level. The inference from this study may be used as reference standard in the further quality control researches.

KEY WORDS: Arogyavardhini Compound, HPTLC,Pharmacognosy, Physicochemical analysis.

Keywords: Therapeutics

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Author Biographies

Bharatkumar Chhaganbhai Padhar, Ph.D Scholar Kayahikitsa Department I.P.G.T and R.A Gujarat Ayurved University Jamnagar 361008

Ph.D ScholarKayahikitsa DepartmentI.P.G.T and R.AGujarat Ayurved UniversityJamnagar 361008

Alankruta R Dave, Associate Prof. & I/C Head of Department of Kayachikitsa, I.P.G.T & R.A, Gujarat Ayurved University Jamnagar, India

Associate Prof. & I/C Head of Department of Kayachikitsa, I.P.G.T & R.A, Gujarat Ayurved University Jamnagar, India

C R Harisha, Head of Pharmacognosy laboratory, I.P.G.T & R.A, Gujarat Ayurved University Jamnagar, India
Head of Pharmacognosy laboratory, I.P.G.T & R.A, Gujarat Ayurved University Jamnagar, India
V J Shukla, Head of Pharmaceutical laboratory, I.P.G.T & R.A, Gujarat Ayurved University Jamnagar, India

Head of Pharmaceutical laboratory, I.P.G.T & R.A, Gujarat Ayurved University Jamnagar, India

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Padhar B, Dave A, Harisha C, Shukla V. PRELIMINARY PHARMACOGNOSTICAL AND PHYTOCHEMICAL EVALUATION OF AROGYAVARDHINI COMPOUND- AN EMERGING FORMULATED MEDICINE FOR METABOLIC SYNDROME. JDDT [Internet]. 15Jan.2016 [cited 27Feb.2020];6(1):46-0. Available from: http://jddtonline.info/index.php/jddt/article/view/1185